Revolutionizing Cervical Cancer Screening: Self-Vaginal Sampling for Human Papillomavirus Detection.

Self-vaginal sampling (SVS) is a promising tool for cervical cancer prevention, offering a convenient and cost-effective alternative to traditional screening. With an 80% lifetime risk of HPV infection among women, SVS improves accessibility, particularly for marginalized communities and older women who are often excluded from routine screening. It reduces discomfort, empowers self-care, and provides insights into the vaginal microbiome, aiding in the detection of pathogens beyond HPV. However, challenges such as loss to follow-up, sampling errors, and misconceptions persist. Despite these hurdles, SVS remains a vital strategy for increasing screening participation and reducing cervical cancer disparities.