Mansoor Ahmad Bhat , Tanja Radu , Ignacio Martín-Fabiani , Panagiotis D. Kolokathis , Anastasios G. Papadiamantis , Stephan Wagner , Yvonne Kohl , Hilda Witters , Wouter A. Gebbink , Yentl Pareja Rodriguez , Giuseppe Cardelini , Roel Degens , Ivana Burzic , Beatriz Alfaro Serrano , Claudia Pretschuh , Eduardo Santamaría-Aranda , Elena Contreras-García , Judith Sinic , Christoph Jocham , Dror Cohen , Milica Velimirovic
{"title":"安全可持续的新一代化学品和材料设计:SSbD4CheM项目在纺织、化妆品和汽车领域的创新","authors":"Mansoor Ahmad Bhat , Tanja Radu , Ignacio Martín-Fabiani , Panagiotis D. Kolokathis , Anastasios G. Papadiamantis , Stephan Wagner , Yvonne Kohl , Hilda Witters , Wouter A. Gebbink , Yentl Pareja Rodriguez , Giuseppe Cardelini , Roel Degens , Ivana Burzic , Beatriz Alfaro Serrano , Claudia Pretschuh , Eduardo Santamaría-Aranda , Elena Contreras-García , Judith Sinic , Christoph Jocham , Dror Cohen , Milica Velimirovic","doi":"10.1016/j.csbj.2025.03.022","DOIUrl":null,"url":null,"abstract":"<div><div>The strategic objective of the Safe and sustainable by design of next generation chemicals and materials (SSbD4CheM) project is to develop screening and testing strategies for a variety of substances and materials to ensure safer and more sustainable products in line with the Sustainable Products Initiative. SSbD4CHeM is focusing on chemical safety using new approach methods, including <em>in vitro</em> studies without animal models and <em>in silico</em> tools. Additionally, it integrates environmental sustainability for the implementation of the Safe and Sustainable by Design (SSbD) framework including risk assessment and <em>ex-ante</em> life cycle assessment. New methods and models for safety and sustainability assessment along chemical, material and product life cycles will be developed, validated, and applied to three case studies, including biobased self-cleaning, water repellent, and antimicrobial treatments for textiles, nanocellulose as an additive in cosmetics, and microcellulose composites for the automotive industry. By employing a multidisciplinary strategy, SSbD4CHeM addresses key challenges in material innovation, ensuring regulatory compliance while reducing hazards to environmental and human health. 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Safe and sustainable by design of next generation chemicals and materials: SSbD4CheM project innovations in the textiles, cosmetic and automotive sectors
The strategic objective of the Safe and sustainable by design of next generation chemicals and materials (SSbD4CheM) project is to develop screening and testing strategies for a variety of substances and materials to ensure safer and more sustainable products in line with the Sustainable Products Initiative. SSbD4CHeM is focusing on chemical safety using new approach methods, including in vitro studies without animal models and in silico tools. Additionally, it integrates environmental sustainability for the implementation of the Safe and Sustainable by Design (SSbD) framework including risk assessment and ex-ante life cycle assessment. New methods and models for safety and sustainability assessment along chemical, material and product life cycles will be developed, validated, and applied to three case studies, including biobased self-cleaning, water repellent, and antimicrobial treatments for textiles, nanocellulose as an additive in cosmetics, and microcellulose composites for the automotive industry. By employing a multidisciplinary strategy, SSbD4CHeM addresses key challenges in material innovation, ensuring regulatory compliance while reducing hazards to environmental and human health. The project will accelerate the development of next-generation sustainable materials, promoting industry innovation, regulatory progress, and improved consumer safety. Ultimately, SSbD4CheM aims to establish a new benchmark for the development of chemicals and materials that conform to safety and sustainability goals.
期刊介绍:
Computational and Structural Biotechnology Journal (CSBJ) is an online gold open access journal publishing research articles and reviews after full peer review. All articles are published, without barriers to access, immediately upon acceptance. The journal places a strong emphasis on functional and mechanistic understanding of how molecular components in a biological process work together through the application of computational methods. Structural data may provide such insights, but they are not a pre-requisite for publication in the journal. Specific areas of interest include, but are not limited to:
Structure and function of proteins, nucleic acids and other macromolecules
Structure and function of multi-component complexes
Protein folding, processing and degradation
Enzymology
Computational and structural studies of plant systems
Microbial Informatics
Genomics
Proteomics
Metabolomics
Algorithms and Hypothesis in Bioinformatics
Mathematical and Theoretical Biology
Computational Chemistry and Drug Discovery
Microscopy and Molecular Imaging
Nanotechnology
Systems and Synthetic Biology