肾脏交换项目公平性方案的适应、比较和实际实施

IF 6 2区 管理学 Q1 OPERATIONS RESEARCH & MANAGEMENT SCIENCE
William St-Arnaud , Margarida Carvalho , Golnoosh Farnadi
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引用次数: 0

摘要

肾脏交换计划(KEPs)通常通过交换供体来最大化患者的整体利益。这种利益的聚合(功利目标)引起了对KEPs中获得移植的潜在个体患者差异的质疑。此外,当前的KEP政策要么全有,要么全无,这意味着只确定一个交换计划——每个患者要么被选中,要么不被选中作为唯一解决方案的一部分。在这项工作中,我们通过在考虑患者处于解决方案中的(事前)概率的交换计划集上寻求抽奖来扩展政策空间。为了指导我们的政策决定,我们将流行的公平方案应用于持续成本计划,以平衡最大化功利目标的通常方法。公平和功利目标的不同组合被建模为具有指数变量数的二次规划。我们提出了一种列生成方法来有效地解决这些问题。最后,我们在效用和公平得分的平衡方面对不同的方案进行了广泛的比较,并验证了我们的方法对文献中基准实例的可扩展性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adaptation, comparison and practical implementation of fairness schemes in Kidney Exchange Programs
Kidney Exchange Programs (KEPs) typically maximize overall patient benefit through donor exchanges. This aggregation of benefits (utilitarian objective) calls into question potential individual patient disparities in terms of access to transplantation in KEPs. Moreover, current KEP policies are all-or-nothing, meaning that only one exchange plan is determined — each patient is either selected or not as part of that unique solution. In this work, we extend the space of policies by seeking a lottery over the set of exchange plans that contemplates the (ex-ante) probability of patients being in a solution. To guide the determination of our policy, we adapt popular fairness schemes to KEPs to balance the usual approach of maximizing the utilitarian objective. Different combinations of fairness and utilitarian objectives are modeled as conic programs with an exponential number of variables. We propose a column generation approach to solve them effectively in practice. Finally, we make an extensive comparison of the different schemes in terms of the balance of utility and fairness score, and validate the scalability of our methodology for benchmark instances from the literature.
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来源期刊
European Journal of Operational Research
European Journal of Operational Research 管理科学-运筹学与管理科学
CiteScore
11.90
自引率
9.40%
发文量
786
审稿时长
8.2 months
期刊介绍: The European Journal of Operational Research (EJOR) publishes high quality, original papers that contribute to the methodology of operational research (OR) and to the practice of decision making.
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