Winifred Maduko, Emmanuel Olamijuwon, Mike Kesby, Jo Mhairi Hale
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This scoping review critically investigates public-targeted interventions on AMR and antibiotic use within SSA, paying close attention to the theories underpinning those interventions. Given the concerning global rise in the spread of AMR and its severe implications, the situation may likely deteriorate if interventions are not significantly enhanced.</p><p><strong>Methods: </strong>A comprehensive search of peer-reviewed literature published in three databases (PubMed, Web of Science and Google Scholar) between 1997 and 2023 was conducted to determine the extent, range and nature of existing studies in this area. This review used the Arksey and O'Malley five-step scoping review framework.</p><p><strong>Results: </strong>The final review included seven publications, with three of the studies conducted in Ghana and the remaining studies carried out across other SSA nations. Findings revealed that AMR interventions were tailored to various demographics, including school children, parents, patients and online audiences. There is a notable lack of inclusive interventions for vulnerable populations, such as persons living with disabilities.</p><p><strong>Conclusion: </strong>The study findings emphasise the critical need for more community-centred research and AMR interventions that integrate relevant theoretical frameworks while being appropriately tailored to local contexts.</p>","PeriodicalId":9137,"journal":{"name":"BMJ Global Health","volume":"10 3","pages":""},"PeriodicalIF":7.1000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931924/pdf/","citationCount":"0","resultStr":"{\"title\":\"Public-targeted interventions addressing antimicrobial resistance and antibiotic use in Sub-Saharan Africa: a scoping review.\",\"authors\":\"Winifred Maduko, Emmanuel Olamijuwon, Mike Kesby, Jo Mhairi Hale\",\"doi\":\"10.1136/bmjgh-2024-017455\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Antimicrobial resistance (AMR) is a global health threat, with sub-Saharan Africa (SSA) experiencing the heaviest health burden and the highest AMR-related mortality. 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引用次数: 0
摘要
抗菌素耐药性（AMR）是一个全球性的健康威胁，撒哈拉以南非洲（SSA）面临着最沉重的健康负担和最高的AMR相关死亡率。该地区的大多数干预措施侧重于医院环境和提供者行为，很少有实证论文讨论理论如何具体告知这些干预措施，以社区为中心的干预措施往往缺乏理论框架。然而，使用行为改变理论可以帮助我们了解公众对抗生素使用的行为，以及如何开发基于理论的干预措施以最大限度地提高有效性。这一范围审查批判性地调查了SSA内针对抗菌素耐药性和抗生素使用的公共干预措施，并密切关注支撑这些干预措施的理论。鉴于抗菌素耐药性在全球范围内的蔓延及其严重影响令人担忧，如果不大力加强干预措施，情况可能会恶化。方法：对1997年至2023年间在PubMed、Web of Science和谷歌Scholar三个数据库中发表的同行评议文献进行全面检索，以确定该领域现有研究的程度、范围和性质。本综述使用了Arksey和O'Malley的五步范围评估框架。结果：最终审查包括7篇出版物，其中3篇研究在加纳进行，其余研究在其他SSA国家进行。调查结果显示，抗菌素耐药性干预措施是针对各种人口统计数据量身定制的，包括学童、家长、患者和在线观众。明显缺乏针对弱势群体（如残疾人）的包容性干预措施。结论：研究结果强调，迫切需要更多以社区为中心的研究和抗菌素耐药性干预措施，这些研究和干预措施应结合相关理论框架，同时适当地根据当地情况进行调整。
Public-targeted interventions addressing antimicrobial resistance and antibiotic use in Sub-Saharan Africa: a scoping review.
Introduction: Antimicrobial resistance (AMR) is a global health threat, with sub-Saharan Africa (SSA) experiencing the heaviest health burden and the highest AMR-related mortality. Most interventions in the region focus on hospital settings and provider behaviour, with few empirical papers discussing how theories inform those interventions specifically, community-centred interventions often lack a theoretical framework. However, using behavioural change theories can help us understand public behaviour around antibiotic usage and how to develop theoretically based interventions to maximise effectiveness. This scoping review critically investigates public-targeted interventions on AMR and antibiotic use within SSA, paying close attention to the theories underpinning those interventions. Given the concerning global rise in the spread of AMR and its severe implications, the situation may likely deteriorate if interventions are not significantly enhanced.
Methods: A comprehensive search of peer-reviewed literature published in three databases (PubMed, Web of Science and Google Scholar) between 1997 and 2023 was conducted to determine the extent, range and nature of existing studies in this area. This review used the Arksey and O'Malley five-step scoping review framework.
Results: The final review included seven publications, with three of the studies conducted in Ghana and the remaining studies carried out across other SSA nations. Findings revealed that AMR interventions were tailored to various demographics, including school children, parents, patients and online audiences. There is a notable lack of inclusive interventions for vulnerable populations, such as persons living with disabilities.
Conclusion: The study findings emphasise the critical need for more community-centred research and AMR interventions that integrate relevant theoretical frameworks while being appropriately tailored to local contexts.
期刊介绍：
BMJ Global Health is an online Open Access journal from BMJ that focuses on publishing high-quality peer-reviewed content pertinent to individuals engaged in global health, including policy makers, funders, researchers, clinicians, and frontline healthcare workers. The journal encompasses all facets of global health, with a special emphasis on submissions addressing underfunded areas such as non-communicable diseases (NCDs). It welcomes research across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or specialized studies. The journal also encourages opinionated discussions on controversial topics.
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