B O Ogunbosi, A Kigbu, O O Tongo, A A Adepoju, A E Orimadegun, G N Odaibo, D O Olaleye, O O Akinyinka
{"title":"Emergence of <i>Raoultella ornithinolytica</i> as a significant intestinal microbiota in Nigerian Neonates.","authors":"B O Ogunbosi, A Kigbu, O O Tongo, A A Adepoju, A E Orimadegun, G N Odaibo, D O Olaleye, O O Akinyinka","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>There are increasing reports of <i>Raoultella ornithinolytica</i> infection in humans. This study reports significant contribution of <i>Raoultella ornithinolytica</i> to neonatal gut microbiota.</p><p><strong>Methods: </strong>Rectal swab samples were collected in 70 healthy neonates, within 6-12hours of birth, and days 3, 9, and 14 after birth. Colonization by <i>R. ornithinolytica</i> was evaluated against neonatal characteristics.</p><p><strong>Results: </strong>Among the 70 neonates, <i>R. ornithinolytica</i> was the fourth most common bacteria isolated. <i>R. ornithinolytica</i> was part of gut microbiota at birth, and on Day 3, Day 9 and Day 14 after birth in 15%, 28.6%, 21.4% and 5.7% of neonates respectively. No factor was associated with <i>R. ornithinolytica</i> colonization, but a trend towards an increased likelihood of colonization among females, asphyxiated and neonates whose mothers had prolonged labour was observed.</p><p><strong>Conclusion: </strong><i>R. ornithinolytica</i> has emerged as an important part of gut microbiota among neonates in Nigeria, but its' role in neonatal dysbiosis and infection remains unclear.</p>","PeriodicalId":101373,"journal":{"name":"African journal of medicine and medical sciences","volume":"52 4","pages":"247-253"},"PeriodicalIF":0.0000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907646/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"African journal of medicine and medical sciences","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Emergence of Raoultella ornithinolytica as a significant intestinal microbiota in Nigerian Neonates.
Background: There are increasing reports of Raoultella ornithinolytica infection in humans. This study reports significant contribution of Raoultella ornithinolytica to neonatal gut microbiota.
Methods: Rectal swab samples were collected in 70 healthy neonates, within 6-12hours of birth, and days 3, 9, and 14 after birth. Colonization by R. ornithinolytica was evaluated against neonatal characteristics.
Results: Among the 70 neonates, R. ornithinolytica was the fourth most common bacteria isolated. R. ornithinolytica was part of gut microbiota at birth, and on Day 3, Day 9 and Day 14 after birth in 15%, 28.6%, 21.4% and 5.7% of neonates respectively. No factor was associated with R. ornithinolytica colonization, but a trend towards an increased likelihood of colonization among females, asphyxiated and neonates whose mothers had prolonged labour was observed.
Conclusion: R. ornithinolytica has emerged as an important part of gut microbiota among neonates in Nigeria, but its' role in neonatal dysbiosis and infection remains unclear.
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