免疫功能低下患者肺部非结核分枝杆菌感染的挑战日益增加:流行病学和治疗。

IF 2.9 4区 医学 Q3 IMMUNOLOGY
Archivum Immunologiae et Therapiae Experimentalis Pub Date : 2025-03-14 eCollection Date: 2025-01-01 DOI:10.2478/aite-2025-0005
Weronika Burzyńska, Marek Fol, Magdalena Druszczynska
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引用次数: 0

摘要

非结核分枝杆菌(NTM)越来越被认为是人类和动物中的机会性病原体,尤其影响免疫系统受损的人。这些细菌包括多种分枝杆菌种类,可导致一系列感染,肺部和皮肤相关疾病是最常见的。近年来NTM感染的上升日益引起卫生保健的关注,突出表明迫切需要提高我们对NTM流行病学和治疗策略的理解。本文综述了与免疫功能低下患者肺部感染相关的NTM物种,并强调了推进诊断和治疗方法的重要性。该评论基于对PubMed、Scopus和ScienceDirect等数据库中科学文献的全面分析,涵盖了截至2024年6月的研究。通过这一综合分析,本文旨在提供对NTM疾病复杂性的详细见解,并促进在对抗这些具有挑战性的感染方面的进一步研究和创新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Growing Challenges of Lung Infections with Non-tuberculous Mycobacteria in Immunocompromised Patients: Epidemiology and Treatment.

Non-tuberculous mycobacteria (NTM) are increasingly recognized as opportunistic pathogens in humans and animals, particularly affecting those with compromised immune systems. These bacteria encompass a diverse group of mycobacterial species that are responsible for a range of infections, with pulmonary and skin-related conditions being the most common. The rise in NTM infections in recent years is a growing concern for healthcare, highlighting the urgent need to improve our understanding of NTM epidemiology and treatment strategies. This article reviews the NTM species associated with lung infections in immunocompromised patients and underscores the critical importance of advancing diagnostic and therapeutic approaches. The review is based on a thorough analysis of scientific literature from databases such as PubMed, Scopus, and ScienceDirect, covering studies up to June 2024. Through this comprehensive analysis, the article aims to provide detailed insights into the complexities of NTM diseases and spur further research and innovation in combating these challenging infections.

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来源期刊
CiteScore
5.90
自引率
0.00%
发文量
26
审稿时长
>12 weeks
期刊介绍: Archivum Immunologiae et Therapiae Experimentalis (AITE), founded in 1953 by Ludwik Hirszfeld, is a bimonthly, multidisciplinary journal. It publishes reviews and full original papers dealing with immunology, experimental therapy, immunogenetics, transplantation, microbiology, immunochemistry and ethics in science.
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