{"title":"利用蒙特卡罗模拟研究典型3d打印材料在内剂量学中的组织等效性。","authors":"Ayse Karadeniz-Yildirim, Handan Tanyildizi-Kokkulunk","doi":"10.1007/s13246-025-01532-2","DOIUrl":null,"url":null,"abstract":"<p><p>This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy.</p><p><strong>Materials and methods: </strong>A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities.</p><p><strong>Results: </strong>For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs.</p><p><strong>Conclusion: </strong>In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using monte carlo simulations.\",\"authors\":\"Ayse Karadeniz-Yildirim, Handan Tanyildizi-Kokkulunk\",\"doi\":\"10.1007/s13246-025-01532-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy.</p><p><strong>Materials and methods: </strong>A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities.</p><p><strong>Results: </strong>For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs.</p><p><strong>Conclusion: </strong>In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.</p>\",\"PeriodicalId\":48490,\"journal\":{\"name\":\"Physical and Engineering Sciences in Medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-03-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physical and Engineering Sciences in Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s13246-025-01532-2\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physical and Engineering Sciences in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s13246-025-01532-2","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using monte carlo simulations.
This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy.
Materials and methods: A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities.
Results: For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs.
Conclusion: In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.
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