Ilia Filipev, Saree Alnaghy, Martin Carolan, Jason Paino, Marco Petasecca, Dean Cutajar, Joel Poder, Justin B. Davies, Bradley M. Oborn, Nicholas Hardcastle, Susanna Guatelli, Michael Lerch, Tomas Kron, Anatoly Rosenfeld
{"title":"“MagicPlates”是一种新的976像素单片硅探测器,用于放射肿瘤学的高空间分辨率剂量测定。","authors":"Ilia Filipev, Saree Alnaghy, Martin Carolan, Jason Paino, Marco Petasecca, Dean Cutajar, Joel Poder, Justin B. Davies, Bradley M. Oborn, Nicholas Hardcastle, Susanna Guatelli, Michael Lerch, Tomas Kron, Anatoly Rosenfeld","doi":"10.1002/acm2.70015","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>We introduce the next generation of “MagicPlate” 2D monolithic pixelated semiconductor detectors – MagicPlate-976 (MP976). It features a larger array area, higher spatial resolution, and does not require external triggering. We perform a comprehensive characterization for small-field steep-dose-gradient dosimetry applications in radiation therapy focusing on x-ray beams used in stereotactic treatments.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>The MP976, developed by the Centre for Medical Radiation Physics, consists of 976 ion-implanted diodes on a thin n-type epitaxial silicon substrate with a total array area of 58 × 58 mm<sup>2</sup>. The central region has “small” diodes with an area of 0.2 × 0.2 mm<sup>2</sup> and 1 mm pitch and the peripheral region has “large” diodes with an area of 0.6 × 0.6 mm<sup>2</sup> and 2 mm pitch. The detector was primed with 10 kGy (Co-60) and tested using a Varian TrueBeam linear accelerator for sensitivity change and dose linearity, and variations in response due to dose-per-pulse and beam incidence angle. Output factors, depth dose, and beam profiles were measured and compared with reference data.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>After the 10 kGy, the sensitivity declined by (74 ± 5)% for “large” diodes and by (78 ± 7)% for the “small” ones, the dose-per-pulse (DPP) dependence was in the range of commercially available diodes, however, a difference in the DPP dependence between the “large” and “small” diodes of (8.4 ± 0.2)% was found in the studied DPP range from 0.131–1.111 mGy/pulse. The minimum angular response was at 90° for 6 MV and 100° for 10 MV flattened beams (76% and 82%, respectively). The output factors and depth dose response showed agreement with the reference within 3.1% and 1%, respectively. Deviation in small field 80%/20% penumbra measurements was within 0.5 mm for 6 MV FF and 0.3 mm for 10 MV FFF. Full width at half maximum (FWHM) for the beam profiles agreed within 0.5 mm for both beam qualities.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>The new MagicPlate-976 detector system is shown to be suitable for dosimetry in small fields and steep dose gradients. It provides 1 mm spatial resolution in the central region and 2 mm on the periphery and has no dependence on the field size. The system's high spatial and temporal resolution opens new opportunities for trigger-less, film-less, and time-resolved verification and error identification for complex stereotactic treatment plans.</p>\n </section>\n </div>","PeriodicalId":14989,"journal":{"name":"Journal of Applied Clinical Medical Physics","volume":"26 4","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm2.70015","citationCount":"0","resultStr":"{\"title\":\"High spatial resolution dosimetry for radiation oncology with “MagicPlates,” a new 976-pixel monolithic silicon detector\",\"authors\":\"Ilia Filipev, Saree Alnaghy, Martin Carolan, Jason Paino, Marco Petasecca, Dean Cutajar, Joel Poder, Justin B. Davies, Bradley M. 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The central region has “small” diodes with an area of 0.2 × 0.2 mm<sup>2</sup> and 1 mm pitch and the peripheral region has “large” diodes with an area of 0.6 × 0.6 mm<sup>2</sup> and 2 mm pitch. The detector was primed with 10 kGy (Co-60) and tested using a Varian TrueBeam linear accelerator for sensitivity change and dose linearity, and variations in response due to dose-per-pulse and beam incidence angle. Output factors, depth dose, and beam profiles were measured and compared with reference data.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>After the 10 kGy, the sensitivity declined by (74 ± 5)% for “large” diodes and by (78 ± 7)% for the “small” ones, the dose-per-pulse (DPP) dependence was in the range of commercially available diodes, however, a difference in the DPP dependence between the “large” and “small” diodes of (8.4 ± 0.2)% was found in the studied DPP range from 0.131–1.111 mGy/pulse. The minimum angular response was at 90° for 6 MV and 100° for 10 MV flattened beams (76% and 82%, respectively). The output factors and depth dose response showed agreement with the reference within 3.1% and 1%, respectively. Deviation in small field 80%/20% penumbra measurements was within 0.5 mm for 6 MV FF and 0.3 mm for 10 MV FFF. Full width at half maximum (FWHM) for the beam profiles agreed within 0.5 mm for both beam qualities.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>The new MagicPlate-976 detector system is shown to be suitable for dosimetry in small fields and steep dose gradients. It provides 1 mm spatial resolution in the central region and 2 mm on the periphery and has no dependence on the field size. 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High spatial resolution dosimetry for radiation oncology with “MagicPlates,” a new 976-pixel monolithic silicon detector
Purpose
We introduce the next generation of “MagicPlate” 2D monolithic pixelated semiconductor detectors – MagicPlate-976 (MP976). It features a larger array area, higher spatial resolution, and does not require external triggering. We perform a comprehensive characterization for small-field steep-dose-gradient dosimetry applications in radiation therapy focusing on x-ray beams used in stereotactic treatments.
Methods
The MP976, developed by the Centre for Medical Radiation Physics, consists of 976 ion-implanted diodes on a thin n-type epitaxial silicon substrate with a total array area of 58 × 58 mm2. The central region has “small” diodes with an area of 0.2 × 0.2 mm2 and 1 mm pitch and the peripheral region has “large” diodes with an area of 0.6 × 0.6 mm2 and 2 mm pitch. The detector was primed with 10 kGy (Co-60) and tested using a Varian TrueBeam linear accelerator for sensitivity change and dose linearity, and variations in response due to dose-per-pulse and beam incidence angle. Output factors, depth dose, and beam profiles were measured and compared with reference data.
Results
After the 10 kGy, the sensitivity declined by (74 ± 5)% for “large” diodes and by (78 ± 7)% for the “small” ones, the dose-per-pulse (DPP) dependence was in the range of commercially available diodes, however, a difference in the DPP dependence between the “large” and “small” diodes of (8.4 ± 0.2)% was found in the studied DPP range from 0.131–1.111 mGy/pulse. The minimum angular response was at 90° for 6 MV and 100° for 10 MV flattened beams (76% and 82%, respectively). The output factors and depth dose response showed agreement with the reference within 3.1% and 1%, respectively. Deviation in small field 80%/20% penumbra measurements was within 0.5 mm for 6 MV FF and 0.3 mm for 10 MV FFF. Full width at half maximum (FWHM) for the beam profiles agreed within 0.5 mm for both beam qualities.
Conclusion
The new MagicPlate-976 detector system is shown to be suitable for dosimetry in small fields and steep dose gradients. It provides 1 mm spatial resolution in the central region and 2 mm on the periphery and has no dependence on the field size. The system's high spatial and temporal resolution opens new opportunities for trigger-less, film-less, and time-resolved verification and error identification for complex stereotactic treatment plans.
期刊介绍:
Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission.
JACMP will publish:
-Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500.
-Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed.
-Technical Notes: These should be no longer than 3000 words, including key references.
-Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents.
-Book Reviews: The editorial office solicits Book Reviews.
-Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics.
-Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic