神经外科急诊的麻醉处理。

IF 2.3 3区 医学 Q2 ANESTHESIOLOGY
Vanessa Bou Sleiman, Bryan Benson, Sam Gumbert
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引用次数: 0

摘要

综述目的:神经麻醉提出了独特的挑战,需要最新的识别和管理知识和多学科合作,以获得最佳的患者结果。这篇综述文章旨在根据当前文献更新和共识建议,提高读者对术中紧急情况的理解和准备。近期研究结果:近年来外伤性脑损伤(TBI)的研究结果强调了控制颅内压(ICP)和维持脑灌注的重要性。然而,它们也挑战了单一针对ICP的干预措施的有效性,表明多模式监测方法的潜在益处。在急性中风的背景下,最近的随机试验表明,与镇静技术相比,全身麻醉(GA)的再通率更高,并发症和长期结局没有显著差异。此外,多项试验和一项荟萃分析表明,与保守的血压目标相比,血管内治疗(EVT)再通后强化血压管理没有益处,而且可能会造成伤害。摘要:神经麻醉紧急情况的最佳管理需要最新的知识、培训和跨学科协调,以确保最佳结果。在过去的两年里,在神经麻醉实践的推进方面,大量的研究工作已经投入到神经麻醉实践中,因此,在多组随机对照试验(rct)以及这些随机对照试验的荟萃分析中,一些基本的管理问题已经受益。这些内容涉及颅脑损伤后颅内间隔综合征的ICP和补充生理监测,EVT的GA与镇静的对比,以及再通后的血压管理。在这篇综述中,我们强调了这项重要的工作,以及进一步完善这些问题的答案的下一步工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anesthetic management of neurosurgical emergencies.

Purpose of review: Neuroanesthesia presents unique challenges that require up-to-date knowledge in identification and management and multidisciplinary collaboration for optimal patient outcomes. This review paper aims to enhance the reader's understanding and preparedness for intraoperative emergencies based on current literature updates and consensus recommendations.

Recent findings: Recent findings in traumatic brain injury (TBI) emphasize the importance of controlling intracranial pressure (ICP) and maintaining cerebral perfusion. However, they also challenge the efficacy of sole ICP targeting interventions, suggesting potential benefits from multimodal monitoring approaches. In the context of acute stroke, recent randomized trials have demonstrated that general anesthesia (GA) compared with sedation techniques results in higher recanalization rates, with no significant difference in complications or long-term outcomes. Furthermore, multiple trials and a meta-analysis have shown that intensive blood pressure management following recanalization with endovascular therapy (EVT) offers no benefit and may impose harm when compared with conservative blood pressure targets.

Summary: Optimal management of neuroanesthetic emergencies requires up-to-date knowledge, training, and interdisciplinary coordination to ensure the best possible outcomes. Significant research effort has been devoted to advancing neuroanesthesia practice, so that in the last 2 years, several fundamental management questions have benefitted from randomized controlled trials (RCTs) from multiple groups, as well as meta-analyses of these RCTs. These address ICP and complementary physiologic monitoring for intracranial compartment syndrome after TBI, GA versus sedation for EVT, and postrecanalization blood pressure management. In this review, we have highlighted this important work as well as the next steps in further refining answers to these questions.

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来源期刊
CiteScore
4.90
自引率
8.00%
发文量
207
审稿时长
12 months
期刊介绍: ​​​​​​​​Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in Anesthesiology features hand-picked review articles from our team of expert editors. With fifteen disciplines published across the year – including cardiovascular anesthesiology, neuroanesthesia and pain medicine – every issue also contains annotated references detailing the merits of the most important papers.
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