中轴性脊柱炎患者颈椎和腰椎活动度与功能能力的关联：来自CASTRO注册中心使用惯性测量单元系统的见解

IF 4.6 2区医学 Q1 RHEUMATOLOGY

Seminars in arthritis and rheumatism Pub Date : 2025-03-03 DOI:10.1016/j.semarthrit.2025.152703

Diana Maria Margareta Moldovan , I. Concepción Aranda-Valera , Lourdes Ladehesa-Pineda , María Carmen Ábalos-Aguilera , María Ángeles Puche-Larrubia , Alejandro Escudero-Contreras , Cristina González-Navas , Juan Luis Garrido-Castro , Daniela Fodor , Eduardo Collantes-Estévez , Clementina López-Medina

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引用次数: 0

摘要

目的本研究旨在利用惯性测量单元（IMU）传感器系统评估轴性脊柱炎（axSpA）患者的颈椎和腰椎活动能力与功能能力的关系，以及疾病持续时间对这种关系的影响。方法本横断面研究包括156例axSpA患者，来自Córdoba axSpA特别工作组注册和结果（CASTRO）登记处。用IMU系统评估脊柱活动度，用巴斯强直性脊柱炎功能指数（BASFI）测量功能能力。根据中位病程将患者分为非长期（≤23年）组和长期（>；23年）组。采用单变量和多变量线性回归来评估每次脊柱运动所解释的BASFI变异性（决定系数[R²]）。结果多变量线性回归分析显示，颈椎活动可解释19.9% （R2 = 0.199）的BASFI变异性，腰椎活动可解释11.3%。在长期axSpA患者中，颈椎旋转（非标准化回归系数[B] = -0.68, 95% CI1.13至-0.24）和腰椎屈曲（B = 0.65, 95% CI 0.05至1.24）与BASFI评分独立相关。在非长期患者中，腰椎活动度，特别是腰椎旋转（B = -0.51, 95% CI0.97至-0.05）与功能能力有更强的相关性。结论：在axSpA患者中，颈椎活动度与功能能力的相关性高于腰椎活动度。然而，颈椎和腰椎活动对功能能力的影响随病程而异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The association of cervical and lumbar mobility with functional ability in axial spondyloarthritis: Insights from the CASTRO registry using Inertial Measurement Unit system

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The association of cervical and lumbar mobility with functional ability in axial spondyloarthritis: Insights from the CASTRO registry using Inertial Measurement Unit system

Objective

This study aimed to evaluate the association of cervical and lumbar mobility with functional ability in patients with axial spondyloarthritis (axSpA) using an inertial measurement unit (IMU) sensor system, as well as the influence of disease duration on this association.

Methods

This cross-sectional study included 156 patients with axSpA from the Córdoba axSpA Task Force Registry and Outcomes (CASTRO) registry. Spinal mobility was assessed with the IMU system and functional ability was measured using the Bath Ankylosing Spondylitis Functional Index (BASFI). Patients were categorized into non-longstanding (≤23 years) and longstanding (>23 years) groups based on the median disease duration. Univariable and multivariable linear regressions were conducted to evaluate the variability of BASFI explained by each spinal movement (coefficient of determination [R²]).

Results

Multivariable linear regression analysis showed that cervical movements collectively explained 19.9 % (R² = 0.199) of BASFI variability, while lumbar mobility accounted for 11.3 %. Among longstanding axSpA patients, cervical rotation (unstandardized regression coefficient [B] = -0.68, 95 % CI1.13 to -0.24) and lumbar flexion (B = 0.65, 95 % CI 0.05 to 1.24), were independently associated with the BASFI scores. In non-longstanding patients, lumbar mobility, particularly lumbar rotation (B = -0.51, 95 % CI0.97 to -0.05), showed a stronger association with functional ability.

Conclusions

This study suggests that cervical mobility is more strongly associated with functional ability than lumbar mobility in axSpA patients. However, the impact of cervical and lumbar mobility on functional ability varies with disease duration.

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来源期刊

Seminars in arthritis and rheumatism 医学-风湿病学

CiteScore

9.20

自引率

4.00%

发文量

176

审稿时长

46 days

期刊介绍： Seminars in Arthritis and Rheumatism provides access to the highest-quality clinical, therapeutic and translational research about arthritis, rheumatology and musculoskeletal disorders that affect the joints and connective tissue. Each bimonthly issue includes articles giving you the latest diagnostic criteria, consensus statements, systematic reviews and meta-analyses as well as clinical and translational research studies. Read this journal for the latest groundbreaking research and to gain insights from scientists and clinicians on the management and treatment of musculoskeletal and autoimmune rheumatologic diseases. The journal is of interest to rheumatologists, orthopedic surgeons, internal medicine physicians, immunologists and specialists in bone and mineral metabolism.