机械功率:使用理想体重来识别有害的机械通气阈值。

IF 2.1 4区 医学 Q2 CRITICAL CARE MEDICINE
Respiratory care Pub Date : 2025-08-01 Epub Date: 2025-03-07 DOI:10.1089/respcare.11815
William M LeTourneau, Alice Gallo De Moraes
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引用次数: 0

摘要

确定呼吸机/通气诱导的肺损伤机制需要了解肺的机械特性以及炎症级联反应所涉及的肺生理学。在床边准确测量代表生理性肺应激和肺应变的参数在临床上具有挑战性。虽然已经提出了肺应力和应变的替代值,如平台压力和驱动压力,但这些值仅代表呼吸机呼吸中的静态变量。有人提出可以用单一变量作为统一参数来确定机械通气安全应用的阈值。“机械动力”的概念将能量负荷转移指定为通风机设置和潮汐量、气道压力和流量的输出。然而,在混合医疗人群中,“绝对”机械动力的使用与体重变化之间存在潜在的脱节。使用理想体重作为表达机械功率的影响因素可能允许更准确地描述施加到肺部的能量和潜在可靠的伤害性机械通气阈值指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mechanical Power: Using Ideal Body Weight to Identify Injurious Mechanical Ventilation Thresholds.

Identifying the mechanisms of ventilator/ventilation-induced lung injury requires an understanding of the pulmonary physiology involved in the mechanical properties of the lung along with the involvement of the inflammatory cascade. Accurately measuring parameters that represent physiologic lung stress and lung strain at the bedside can be clinically challenging. Although surrogates for lung stress and strain have been proposed, such as plateau pressure and driving pressure, these values only represent a static variable in the ventilator breath. It has been proposed that a single variable could be used as a unifying parameter to identify a threshold for the safe application of mechanical ventilation. The concept of "mechanical power" applies an energy load transfer designation to the ventilator settings and output of tidal volume, airway pressures, and flow. However, there is a potential disconnect between the use of "absolute" mechanical power and the variability of body weight throughout a mixed medical population. Using ideal body weight as an influential factor to express mechanical power can potentially allow for a more accurate depiction of energy applied to the lungs and a potentially reliable injurious mechanical ventilation threshold indicator.

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来源期刊
Respiratory care
Respiratory care 医学-呼吸系统
CiteScore
4.70
自引率
16.00%
发文量
209
审稿时长
1 months
期刊介绍: RESPIRATORY CARE is the official monthly science journal of the American Association for Respiratory Care. It is indexed in PubMed and included in ISI''s Web of Science.
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