生物学、临床和社会行为因素与美国细菌性阴道病不成比例的负担相关:一项全面的文献综述。

IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Eren Watkins, Jay Lin, Melissa Lingohr-Smith, Candice Yong, Krishna Tangirala, Kevin Collins
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引用次数: 0

摘要

背景:细菌性阴道病(BV)是一种常见的妇科感染,其特征是阴道微生物群中产生乳酸菌的减少和厌氧菌的增加,与不良健康结果相关。方法:在PubMed检索2012年8月至2022年8月期间发表的关于美国细菌性阴道炎的英文文章,以及导致细菌性阴道炎风险差异的因素,重点是阴道微生物组的作用,确定了760篇文章。结果:在符合预定标准的52篇文章中,BV患病率在不同人群中存在差异,黑人妇女(49% -51%)、西班牙裔妇女(32-43%)和育龄妇女(30%)的影响不成比例。微生物生态和寄主遗传的差异是造成这些差异的重要因素。bv相关细菌的定植在有色人种女性中比在非西班牙裔白人女性中更常见。其他与不成比例负担相关的因素包括多配偶/同性伴侣、肥胖、免疫抑制和剖腹产。结论:细菌性阴道炎的流行是多因素的,一些人群具有较高的患病率和独特的微生物群特征,可能使他们易患此病。由于生物学、临床和社会行为因素的复杂相互作用,BV的治疗和复发预防具有挑战性。了解这些不同的风险因素对于减轻细菌性出血热负担至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biological, Clinical, and Sociobehavioral Factors Associated with Disproportionate Burden of Bacterial Vaginosis in the United States: A Comprehensive Literature Review.

Background: Bacterial vaginosis (BV), a common gynecological infection characterized by reduced lactic acid-producing bacteria and increased anerobic bacteria in the vaginal microbiome, is associated with adverse health outcomes. Methods: A PubMed search for English-language articles about BV in the USA and factors contributing to disparities in BV risk, with an emphasis on the role of the vaginal microbiome, published from August 2012 to August 2022, identified 760 articles. Results: Among the 52 articles meeting the prespecified criteria, BV prevalence varied among different populations and disproportionately impacted Black women (49-51%), Hispanic ethnicity (32-43%), and women of reproductive age (30%). Differences in microbial ecology and host genetics were important factors underlying these disparities. Colonization of BV-associated bacteria was more common in women of color than in non-Hispanic White women. Other factors linked with disproportionate burden included multiple/same-sex partners, obesity, immunosuppression, and C-section birth. Conclusions: BV prevalence was multifactorial, with some populations having higher prevalence rates and distinctive microbiome profiles that may predispose them to the condition. BV treatment and recurrence prevention were challenging due to the complex interplay of biological, clinical, and sociobehavioral factors. Understanding these disparate risk factors is critical to reducing BV burden.

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来源期刊
Journal of women's health
Journal of women's health 医学-妇产科学
CiteScore
6.60
自引率
5.70%
发文量
197
审稿时长
2 months
期刊介绍: Journal of Women''s Health is the primary source of information for meeting the challenges of providing optimal health care for women throughout their lifespan. The Journal delivers cutting-edge advancements in diagnostic procedures, therapeutic protocols for the management of diseases, and innovative research in gender-based biology that impacts patient care and treatment. Journal of Women’s Health coverage includes: -Internal Medicine Endocrinology- Cardiology- Oncology- Obstetrics/Gynecology- Urogynecology- Psychiatry- Neurology- Nutrition- Sex-Based Biology- Complementary Medicine- Sports Medicine- Surgery- Medical Education- Public Policy.
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