晚期癌症患者接近生命终点的预防性药物处方。

IF 1.8 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Internal Medicine Journal Pub Date : 2025-03-08 DOI:10.1111/imj.70013

Jane McKenzie, Catherine Dunn, Grace Gard, Brian Le, Peter Gibbs

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引用次数: 0

摘要

先前的报告表明，许多晚期癌症和有限的预期寿命患者持续使用预防性药物处方（PMP），其益处不确定且风险增加。我们对姑息治疗肿瘤住院患者的回顾发现，尽管入院后16天（四分位数范围10-45）的住院患者中有很高的处方停用率（88%）和死亡率，但首次接受姑息治疗时PMP的发生率（69%）很高。pmp的发生率与上一次全身治疗的时间（P = 0.29）或之前是否参与姑息治疗（P = 0.82）无关。医生和更广泛的多学科护理团队可能会错过绝症患者的去处方机会。

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Preventive medication deprescribing in advanced cancer patients approaching end of life

Previous reports indicated many patients with advanced cancer and limited life expectancy have ongoing preventive medication prescription (PMP) of uncertain benefit and increased risk. Our review of palliative care oncology admissions found high rates of PMP (69%) at time of first palliative care admission, despite high rates of inpatient deprescription (88%) and death at a median of 16 days (interquartile range 10–45) following admission. Rates of PMPs did not vary by time from last systemic treatment (P = 0.29) or by prior palliative care involvement (P = 0.82). Physicians and the wider multidisciplinary care team may be missing deprescription opportunities for terminally ill patients.

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来源期刊

Internal Medicine Journal 医学-医学：内科

CiteScore

3.50

自引率

4.80%

发文量

600

审稿时长

3-6 weeks

期刊介绍： The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.