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引用次数: 0
摘要
本研究旨在评估基于手术出血量、术中最低心率和平均动脉压的外科Apgar评分(SAS)在预测根治性肾切除术(RN)对肾功能的短期和长期影响方面的预测能力。方法:对2016 - 2019年在某三级医院接受肾肿瘤RN治疗的111例患者进行前瞻性调查。计算SAS和年龄校正Charlson合并症指数(CCI)评分与术后第1天、第3和第12个月肾小球滤过率(GFR)变化的关系。结果:高危组患者手术时间较长,住院时间延长,出血量增加,输血率较高(P < 0.001)。sas分层危险组术前与术后早期GFR值差异无统计学意义(P = 0.802, P = 0.342)。术后第3个月(分别为60.79±16.86、76.22±24.20、69.80±18.92)和第12个月(分别为53.57±12.74、71.61±17.52、71.86±19.33),高危组GFR明显低于中、低危组(P = 0.034, P < 0.001)。CCI评分预测低、中、高危组术前GFR(分别为111.58±30.91 ml/min、94.81±22.55 ml/min和85.43±32.69 ml/min)(P = 0.001),但CCI定义的高危组术后第3个月和第12个月GFR变化无统计学意义(P = 0.546, P = 0.481)。结论:在RN手术期间估计的SAS与术后3个月和12个月的GFR变化之间存在显著相关性。基于SAS,高危患者可推荐早期保肾治疗,如饮食和避免肾毒性药物,以防止长期的GFR改变。
期刊介绍:
The Iranian Journal of Kidney Diseases (IJKD), a peer-reviewed journal in English, is the official publication of the Iranian Society of Nephrology. The aim of the IJKD is the worldwide reflection of the knowledge produced by the scientists and clinicians in nephrology. Published quarterly, the IJKD provides a new platform for advancement of the field. The journal’s objective is to serve as a focal point for debates and exchange of knowledge and experience among researchers in a global context. Original papers, case reports, and invited reviews on all aspects of the kidney diseases, hypertension, dialysis, and transplantation will be covered by the IJKD. Research on the basic science, clinical practice, and socio-economics of renal health are all welcomed by the editors of the journal.