{"title":"与坚持以片剂为基础的认知训练相关的因素：J-MINT研究","authors":"Taiki Sugimoto, Kazuaki Uchida, Kenji Sato, Yoko Yokoyama, Ayaka Onoyama, Kosuke Fujita, Yujiro Kuroda, Satomu Wakayama, Hidenori Arai, Takashi Sakurai, J-MINT study group","doi":"10.1002/trc2.70062","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> INTRODUCTION</h3>\n \n <p>Cognitive training is a key component of multidomain interventions to prevent cognitive decline; however, low adherence remains a challenge. In this post hoc analysis of the Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT), factors associated with cognitive training adherence in older adults with mild cognitive impairment were investigated.</p>\n </section>\n \n <section>\n \n <h3> METHODS</h3>\n \n <p>J-MINT was an 18-month randomized controlled trial. The analyses included 191 participants (intervention group) who completed the trial. Adherence was assessed by calculating the number of days the participants engaged in tablet-based cognitive training for at least 30 min.</p>\n </section>\n \n <section>\n \n <h3> RESULTS</h3>\n \n <p>Vision difficulty and a larger friend network were negatively associated with adherence. Female sex, higher cognitive function, and satisfaction with training tasks and implementation goals were positively associated with adherence.</p>\n </section>\n \n <section>\n \n <h3> DISCUSSION</h3>\n \n <p>The results imply that not only the participants’ characteristics but also the training task design and implementation goal setting (training duration and frequency) are associated with adherence.</p>\n </section>\n \n <section>\n \n <h3> Clinical trial registration number</h3>\n \n <p>This trial was registered with the University hospital Medical Information Network (UMIN) Clinical Trial Registry (UMIN000038671).</p>\n </section>\n \n <section>\n \n <h3> Highlights</h3>\n \n <div>\n <ul>\n \n <li>Factors associated with adherence to cognitive training were evaluated.</li>\n \n <li>Vision difficulty was negatively associated with adherence.</li>\n \n <li>A larger network of friends was negatively associated with adherence.</li>\n \n <li>Female sex and higher cognitive function were positively associated with adherence.</li>\n \n <li>Satisfaction with training tasks and implementation goals was related to adherence.</li>\n </ul>\n </div>\n </section>\n </div>","PeriodicalId":53225,"journal":{"name":"Alzheimer''s and Dementia: Translational Research and Clinical Interventions","volume":"11 1","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/trc2.70062","citationCount":"0","resultStr":"{\"title\":\"Factors associated with adherence to tablet-based cognitive training: J-MINT study\",\"authors\":\"Taiki Sugimoto, Kazuaki Uchida, Kenji Sato, Yoko Yokoyama, Ayaka Onoyama, Kosuke Fujita, Yujiro Kuroda, Satomu Wakayama, Hidenori Arai, Takashi Sakurai, J-MINT study group\",\"doi\":\"10.1002/trc2.70062\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> INTRODUCTION</h3>\\n \\n <p>Cognitive training is a key component of multidomain interventions to prevent cognitive decline; however, low adherence remains a challenge. In this post hoc analysis of the Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT), factors associated with cognitive training adherence in older adults with mild cognitive impairment were investigated.</p>\\n </section>\\n \\n <section>\\n \\n <h3> METHODS</h3>\\n \\n <p>J-MINT was an 18-month randomized controlled trial. The analyses included 191 participants (intervention group) who completed the trial. Adherence was assessed by calculating the number of days the participants engaged in tablet-based cognitive training for at least 30 min.</p>\\n </section>\\n \\n <section>\\n \\n <h3> RESULTS</h3>\\n \\n <p>Vision difficulty and a larger friend network were negatively associated with adherence. Female sex, higher cognitive function, and satisfaction with training tasks and implementation goals were positively associated with adherence.</p>\\n </section>\\n \\n <section>\\n \\n <h3> DISCUSSION</h3>\\n \\n <p>The results imply that not only the participants’ characteristics but also the training task design and implementation goal setting (training duration and frequency) are associated with adherence.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Clinical trial registration number</h3>\\n \\n <p>This trial was registered with the University hospital Medical Information Network (UMIN) Clinical Trial Registry (UMIN000038671).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Highlights</h3>\\n \\n <div>\\n <ul>\\n \\n <li>Factors associated with adherence to cognitive training were evaluated.</li>\\n \\n <li>Vision difficulty was negatively associated with adherence.</li>\\n \\n <li>A larger network of friends was negatively associated with adherence.</li>\\n \\n <li>Female sex and higher cognitive function were positively associated with adherence.</li>\\n \\n <li>Satisfaction with training tasks and implementation goals was related to adherence.</li>\\n </ul>\\n </div>\\n </section>\\n </div>\",\"PeriodicalId\":53225,\"journal\":{\"name\":\"Alzheimer''s and Dementia: Translational Research and Clinical Interventions\",\"volume\":\"11 1\",\"pages\":\"\"},\"PeriodicalIF\":4.9000,\"publicationDate\":\"2025-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/trc2.70062\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alzheimer''s and Dementia: Translational Research and Clinical Interventions\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/trc2.70062\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alzheimer''s and Dementia: Translational Research and Clinical Interventions","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/trc2.70062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Factors associated with adherence to tablet-based cognitive training: J-MINT study
INTRODUCTION
Cognitive training is a key component of multidomain interventions to prevent cognitive decline; however, low adherence remains a challenge. In this post hoc analysis of the Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT), factors associated with cognitive training adherence in older adults with mild cognitive impairment were investigated.
METHODS
J-MINT was an 18-month randomized controlled trial. The analyses included 191 participants (intervention group) who completed the trial. Adherence was assessed by calculating the number of days the participants engaged in tablet-based cognitive training for at least 30 min.
RESULTS
Vision difficulty and a larger friend network were negatively associated with adherence. Female sex, higher cognitive function, and satisfaction with training tasks and implementation goals were positively associated with adherence.
DISCUSSION
The results imply that not only the participants’ characteristics but also the training task design and implementation goal setting (training duration and frequency) are associated with adherence.
Clinical trial registration number
This trial was registered with the University hospital Medical Information Network (UMIN) Clinical Trial Registry (UMIN000038671).
Highlights
Factors associated with adherence to cognitive training were evaluated.
Vision difficulty was negatively associated with adherence.
A larger network of friends was negatively associated with adherence.
Female sex and higher cognitive function were positively associated with adherence.
Satisfaction with training tasks and implementation goals was related to adherence.
期刊介绍：
Alzheimer''s & Dementia: Translational Research & Clinical Interventions (TRCI) is a peer-reviewed, open access,journal from the Alzheimer''s Association®. The journal seeks to bridge the full scope of explorations between basic research on drug discovery and clinical studies, validating putative therapies for aging-related chronic brain conditions that affect cognition, motor functions, and other behavioral or clinical symptoms associated with all forms dementia and Alzheimer''s disease. The journal will publish findings from diverse domains of research and disciplines to accelerate the conversion of abstract facts into practical knowledge: specifically, to translate what is learned at the bench into bedside applications. The journal seeks to publish articles that go beyond a singular emphasis on either basic drug discovery research or clinical research. Rather, an important theme of articles will be the linkages between and among the various discrete steps in the complex continuum of therapy development. For rapid communication among a multidisciplinary research audience involving the range of therapeutic interventions, TRCI will consider only original contributions that include feature length research articles, systematic reviews, meta-analyses, brief reports, narrative reviews, commentaries, letters, perspectives, and research news that would advance wide range of interventions to ameliorate symptoms or alter the progression of chronic neurocognitive disorders such as dementia and Alzheimer''s disease. The journal will publish on topics related to medicine, geriatrics, neuroscience, neurophysiology, neurology, psychiatry, clinical psychology, bioinformatics, pharmaco-genetics, regulatory issues, health economics, pharmacoeconomics, and public health policy as these apply to preclinical and clinical research on therapeutics.
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