[巨噬细胞在肌腱骨愈合中的作用机制研究进展]。

细胞与分子免疫学杂志 Pub Date : 2025-02-01
Liang Wang, Yinshuan Deng, Tao Qu, Chaoming Da, Yunfei He, Rui Liu, Weimin Niu, Weishun Yan, Zhen Chen, Shuo Li, Zhiyun Yang, Binbin Guo, Xueqian Lai
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引用次数: 0

摘要

肌腱和骨骼之间的连接称为肌腱骨连接。随着国民体育意识的不断提高,过度的运动及相关强度容易造成肌腱骨连接的损伤。肌腱骨愈合是一个涉及多因素的复杂修复和愈合过程,良好的肌腱骨愈合是其生理功能的前提。肌腱骨结构的复杂性也对肌腱骨损伤的修复提出了很大的挑战。近年来研究发现,干细胞、生长因子、巨噬细胞等因素与肌腱骨损伤的愈合过程密切相关,其中巨噬细胞在愈合过程中发挥着重要作用。作者回顾了近年来的相关研究文献,总结了巨噬细胞在肌腱骨愈合中的作用,以期为促进肌腱骨愈合的治疗策略提供新的思路和方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research progresses on the mechanism of macrophages in tendon bone healing].

The connection between tendons and bones is called the tendon bone connection. With the continuous improvement of national sports awareness, excessive exercises and the related intensity are prone to damage the tendon bone connection. Tendon bone healing is a complex repair and healing process involving multiple factors, and good tendon bone healing is a prerequisite for its physiological function. The complexity of tendon bone structure also poses great challenges to the repair of tendon bone injuries. In recent years, researches have found that stem cells, growth factors, macrophages, and other factors are closely related to the healing process of tendon bone injuries, among which macrophages play an important role in the healing process. The authors reviewed relevant research literature in recent years and summarized the role of macrophages in tendon bone healing, in order to provide new ideas and directions for treatment strategies to promote tendon bone healing.

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