Sharmila Patil, Manjyot Gautam, Divya Shetty, Surekha Bhalekar, S Sudhamani
{"title":"原发性皮肤cd8阳性t细胞淋巴瘤-蕈样肉芽肿性真菌病:罕见病例报告。","authors":"Sharmila Patil, Manjyot Gautam, Divya Shetty, Surekha Bhalekar, S Sudhamani","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Granulomatous mycosis fungoides (GMF) is a rare subtype of T-cell cutaneous lymphoma. Due to the lack of distinct clinical features, GMF may pose a diagnostic challenge, which results in diagnostic delay. The diagnosis is based on histopathological and immunohistochemical findings. Herein, we present an 82-year-old male with itchy lesions over the scalp, face, forearms, trunk, and bilateral lower limbs for 6 months. Histologically, it was a CD8-positive GMF. GMF is a rare subtype of mycosis fungoides with <100 cases in the literature, and most of these cases showed a CD4-positive phenotype. CD8-positive GMF is extremely rare. We observed that it commonly affects elderly females. The patients often present with nodules and do not carry an adverse prognosis.</p>","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"19 2","pages":"78-81"},"PeriodicalIF":2.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877052/pdf/","citationCount":"0","resultStr":"{\"title\":\"Primary cutaneous CD8-positive T-cell lymphoma-granulomatous mycosis fungoides: A rare case report.\",\"authors\":\"Sharmila Patil, Manjyot Gautam, Divya Shetty, Surekha Bhalekar, S Sudhamani\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Granulomatous mycosis fungoides (GMF) is a rare subtype of T-cell cutaneous lymphoma. Due to the lack of distinct clinical features, GMF may pose a diagnostic challenge, which results in diagnostic delay. The diagnosis is based on histopathological and immunohistochemical findings. Herein, we present an 82-year-old male with itchy lesions over the scalp, face, forearms, trunk, and bilateral lower limbs for 6 months. Histologically, it was a CD8-positive GMF. GMF is a rare subtype of mycosis fungoides with <100 cases in the literature, and most of these cases showed a CD4-positive phenotype. CD8-positive GMF is extremely rare. We observed that it commonly affects elderly females. The patients often present with nodules and do not carry an adverse prognosis.</p>\",\"PeriodicalId\":47093,\"journal\":{\"name\":\"International Journal of Health Sciences-IJHS\",\"volume\":\"19 2\",\"pages\":\"78-81\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877052/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Health Sciences-IJHS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Health Sciences-IJHS","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Primary cutaneous CD8-positive T-cell lymphoma-granulomatous mycosis fungoides: A rare case report.
Granulomatous mycosis fungoides (GMF) is a rare subtype of T-cell cutaneous lymphoma. Due to the lack of distinct clinical features, GMF may pose a diagnostic challenge, which results in diagnostic delay. The diagnosis is based on histopathological and immunohistochemical findings. Herein, we present an 82-year-old male with itchy lesions over the scalp, face, forearms, trunk, and bilateral lower limbs for 6 months. Histologically, it was a CD8-positive GMF. GMF is a rare subtype of mycosis fungoides with <100 cases in the literature, and most of these cases showed a CD4-positive phenotype. CD8-positive GMF is extremely rare. We observed that it commonly affects elderly females. The patients often present with nodules and do not carry an adverse prognosis.