巨噬细胞治疗和肝脏再生：结果和观点。

IF 2.6 4区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Clinics and research in hepatology and gastroenterology Pub Date : 2025-03-03 DOI:10.1016/j.clinre.2025.102569

Nicolas Lanthier , Laurent Spahr

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引用次数: 0

摘要

最近的一项研究评估了巨噬细胞移植对肝硬化的影响，目的是改善肝功能，这项研究的结果开辟了许多前景。虽然结果是负面的，但观察到的死亡人数减少了，细胞因子谱也有所改善。这与其他肝病研究结果一致，特别是通过对人类肝组织的信号传导和再生研究。未来，如果我们要在这一引人入胜的领域取得进展，还需要回答许多问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Macrophage therapy and liver regeneration: Results and perspectives

The recent results of the study evaluating the impact of macrophage transplantation in cirrhosis with the aim of improving liver function open up a number of prospects. Although negative, fewer deaths were observed, as well as a favourable cytokine profile. This is in line with other results obtained in liver disease, notably through signalling and regeneration studies on human liver tissue. For the future, a number of questions need to be answered if we are to make progress in this fascinating field.

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来源期刊

Clinics and research in hepatology and gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

4.30

自引率

3.70%

发文量

198

审稿时长

42 days

期刊介绍： Clinics and Research in Hepatology and Gastroenterology publishes high-quality original research papers in the field of hepatology and gastroenterology. The editors put the accent on rapid communication of new research and clinical developments and so called "hot topic" issues. Following a clear Editorial line, besides original articles and case reports, each issue features editorials, commentaries and reviews. The journal encourages research and discussion between all those involved in the specialty on an international level. All articles are peer reviewed by international experts, the articles in press are online and indexed in the international databases (Current Contents, Pubmed, Scopus, Science Direct). Clinics and Research in Hepatology and Gastroenterology is a subscription journal (with optional open access), which allows you to publish your research without any cost to you (unless you proactively chose the open access option). Your article will be available to all researchers around the globe whose institution has a subscription to the journal.