新型可穿戴传感器血液中挥发性有机化合物的无创生物荧光传感与成像分析

IF 0.4 4区工程技术 Q4 ENGINEERING, ELECTRICAL & ELECTRONIC

Electrical Engineering in Japan Pub Date : 2025-01-02 DOI:10.1002/eej.23490

Kohji Mitsubayashi

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引用次数: 0

摘要

血液中含有与疾病和代谢相关的挥发性生物标志物。我们开发了一种生物荧光气体传感器，测量丙酮具有高灵敏度，并证实了其在脂质代谢和糖尿病中应用于呼吸测量的意义。此外，针对从血液中渗透到皮肤中的经皮气体，开发了以乙醇蒸气为目标化学物质的生物荧光气体成像系统，并分析了每个皮肤部位经皮气体的分泌动态，从而显示了从耳道稳定释放血液来源的挥发性标记物。在此基础上，我们开发了一种耳机式气体传感器，并成功地进行了连续稳定的经皮气体测量，从而表明了一种新型可穿戴血液voc生物传感器的未来潜力。

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Noninvasive Biofluorometric Sensing and Imaging Analysis of Blood VOCs for Novel Wearable Sensor

Blood contains volatile biomarkers related to diseases and metabolism. We developed a biofluorometric gas sensor that measures acetone with high sensitivity and confirmed its significance in lipid metabolism and diabetes when applied to breath measurement. Furthermore, regarding transcutaneous gases that permeate through the skin from blood, a biofluorometric gas-imaging system for ethanol vapor as the target chemical was developed and analyzed the secretion dynamics of transcutaneous gases at each skin site, thus showing the stable release of blood-derived volatile markers from the ear canal. Based on the results, we have developed a headphone-type gas sensor and succeeded in continuous and stable transcutaneous gas measurement, thus indicating the future potential of a novel wearable biosensor for blood VOCs.

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来源期刊

Electrical Engineering in Japan 工程技术-工程：电子与电气

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Electrical Engineering in Japan (EEJ) is an official journal of the Institute of Electrical Engineers of Japan (IEEJ). This authoritative journal is a translation of the Transactions of the Institute of Electrical Engineers of Japan. It publishes 16 issues a year on original research findings in Electrical Engineering with special focus on the science, technology and applications of electric power, such as power generation, transmission and conversion, electric railways (including magnetic levitation devices), motors, switching, power economics.