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IF 4.6 2区医学 Q1 RHEUMATOLOGY

Seminars in arthritis and rheumatism Pub Date : 2025-02-26 DOI:10.1016/j.semarthrit.2025.152683

Albert J R Heck

引用次数: 0

摘要

IgM 是一种重要的人类免疫球蛋白，不仅存在于我们的血液中，还存在于粘膜和体液（如唾液、眼泪和母乳）中。在这份手稿中，赫克描述了最近的发现，即 CD5L 蛋白总是附着在循环型 IgM 上，而不附着在分泌型 IgM 上。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Distinct appearances of circulatory and secretory IgM demarcated by CD5L.

IgM is an important human immunoglobulin present in our blood, but also in mucosa and body fluids such as saliva, tears and breast milk. In this manuscript Heck describes recent findings, namely that the CD5L protein is always attached to circulatory IgM but not to secretory IgM.

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来源期刊

Seminars in arthritis and rheumatism 医学-风湿病学

CiteScore

9.20

自引率

4.00%

发文量

176

审稿时长

46 days

期刊介绍： Seminars in Arthritis and Rheumatism provides access to the highest-quality clinical, therapeutic and translational research about arthritis, rheumatology and musculoskeletal disorders that affect the joints and connective tissue. Each bimonthly issue includes articles giving you the latest diagnostic criteria, consensus statements, systematic reviews and meta-analyses as well as clinical and translational research studies. Read this journal for the latest groundbreaking research and to gain insights from scientists and clinicians on the management and treatment of musculoskeletal and autoimmune rheumatologic diseases. The journal is of interest to rheumatologists, orthopedic surgeons, internal medicine physicians, immunologists and specialists in bone and mineral metabolism.