利用小管回缩系统进入第四脑室治疗成神经管细胞瘤:一种避免小儿解剖并发症的微创技术的可行性。

IF 0.9 4区 医学 Q4 CLINICAL NEUROLOGY
J Javier Cuéllar-Hernández, Omar R Ortega-Ruiz, Luis Alejandro Pérez-Ruano, Paulo Tabera-Tarello, Javier Terrazo-Lluch
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引用次数: 0

摘要

髓母细胞瘤是儿童最常见的恶性肿瘤。目前的治疗方法包括最大限度的安全切除、化疗和放疗。与其他后窝肿瘤相比,这些患者的生活质量和术后并发症预后较差。因此,手术入路应量身定制,以减少伴随术后并发症(如小脑性缄默症)的可能性。微创技术与管状牵开器已经描述了幕上病变。然而,关于后窝病变的证据仍然很少。同样,也没有在儿科患者中使用这些技术的可用报告。我们报告一例11岁女孩患成神经管细胞瘤的病例。选择了一种不成熟的方法来降低术后小脑缄默症的风险。在2年的随访中,患者无症状,没有小脑症状,也没有病变复发。结论我们报告了本中心首例髓母细胞瘤采用管状孔治疗的病例,旨在探讨其治疗小儿后窝肿瘤的可行性。据我们所知,这是首例经颅手术治疗小儿髓母细胞瘤的报道。小儿小管切除术是一种可行且可重复的方法,可降低解剖结构损伤和小脑缄默症的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Infradentate Approach to the Fourth Ventricle with Tubular Retraction System for Medulloblastoma: Feasibility of a Minimally Invasive Technique to Avoid Anatomical Complications in a Pediatric Patient.

Introduction: Medulloblastoma is the most common malignant tumor in the pediatric population. Current treatment of these lesions includes maximum safe resection, chemotherapy, and radiotherapy. Quality of life for these patients as well as postoperative complications remains with poorer prognosis compared to other posterior fossa tumors. Therefore, the surgical approach should be tailored to diminish the probability of coursing with postoperative complications such as cerebellar mutism. Minimally invasive techniques with tubular retractors have been described for supratentorial lesions. However, evidence remains scarce for lesions in the posterior fossa. Similarly, there are no available reports of the use of these techniques in pediatric patients.

Case presentation: We present the case of an 11-year-old girl with a medulloblastoma. An infradentate approach was elected as the course of action looking to reduce the risk of postoperative cerebellar mutism syndrome. In the 2-year follow-up, the patient remained asymptomatic with no cerebellar signs nor recurrence of the lesion.

Conclusion: We present the first case of a medulloblastoma treated with tubular ports in our center looking to discuss its feasibility for the treatment of posterior fossa tumors in pediatric patients. To the best of our knowledge, this is the first report of transcranial ports used in a pediatric patient for the resection of a medulloblastoma. Infradentate tubular resection could be a feasible and reproducible approach in pediatric patients, reducing the risk of injury to anatomical structures and cerebellar mutism.

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来源期刊
Pediatric Neurosurgery
Pediatric Neurosurgery 医学-临床神经学
CiteScore
1.30
自引率
0.00%
发文量
45
审稿时长
>12 weeks
期刊介绍: Articles in ''Pediatric Neurosurgery'' strives to publish new information and observations in pediatric neurosurgery and the allied fields of neurology, neuroradiology and neuropathology as they relate to the etiology of neurologic diseases and the operative care of affected patients. In addition to experimental and clinical studies, the journal presents critical reviews which provide the reader with an update on selected topics as well as case histories and reports on advances in methodology and technique. This thought-provoking focus encourages dissemination of information from neurosurgeons and neuroscientists around the world that will be of interest to clinicians and researchers concerned with pediatric, congenital, and developmental diseases of the nervous system.
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