{"title":"【新诊断的非急性早幼粒细胞白血病合并弥散性血管内凝血1例报告及文献复习】。","authors":"M Zhou, J Chen, Y Han","doi":"10.3760/cma.j.cn121090-20241129-00499","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective:</b> Disseminated intravascular coagulation (DIC) is common in newly diagnosed acute promyelocytic leukemia (APL), with a high mortality rate. This case report focuses on a successful treatment of non-APL complicated with DIC, aiming to enhance clinical physicians' awareness and diagnostic skills in managing non-APL complicated by DIC. <b>Methods:</b> The diagnosis and treatment of a non-APL patient with DIC was detailed and related literature was reviewed. <b>Results:</b> With the help of early identification of DIC, chemotherapy and supportive treatment, the patient successfully recovered from DIC and achieved complete remission after induction therapy. He achieved long-term survival via subsequent hematopoietic stem cell transplantation. <b>Conclusion:</b> Non-APL patients with DIC are critically severe and early identification and timely intervention are necessary for them.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"22-25"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Newly diagnosed non-acute promyelocytic leukemia combined with disseminated intravascular coagulation: a case report and literature review].\",\"authors\":\"M Zhou, J Chen, Y Han\",\"doi\":\"10.3760/cma.j.cn121090-20241129-00499\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objective:</b> Disseminated intravascular coagulation (DIC) is common in newly diagnosed acute promyelocytic leukemia (APL), with a high mortality rate. This case report focuses on a successful treatment of non-APL complicated with DIC, aiming to enhance clinical physicians' awareness and diagnostic skills in managing non-APL complicated by DIC. <b>Methods:</b> The diagnosis and treatment of a non-APL patient with DIC was detailed and related literature was reviewed. <b>Results:</b> With the help of early identification of DIC, chemotherapy and supportive treatment, the patient successfully recovered from DIC and achieved complete remission after induction therapy. He achieved long-term survival via subsequent hematopoietic stem cell transplantation. <b>Conclusion:</b> Non-APL patients with DIC are critically severe and early identification and timely intervention are necessary for them.</p>\",\"PeriodicalId\":24016,\"journal\":{\"name\":\"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi\",\"volume\":\"45 S1\",\"pages\":\"22-25\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3760/cma.j.cn121090-20241129-00499\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/cma.j.cn121090-20241129-00499","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Newly diagnosed non-acute promyelocytic leukemia combined with disseminated intravascular coagulation: a case report and literature review].
Objective: Disseminated intravascular coagulation (DIC) is common in newly diagnosed acute promyelocytic leukemia (APL), with a high mortality rate. This case report focuses on a successful treatment of non-APL complicated with DIC, aiming to enhance clinical physicians' awareness and diagnostic skills in managing non-APL complicated by DIC. Methods: The diagnosis and treatment of a non-APL patient with DIC was detailed and related literature was reviewed. Results: With the help of early identification of DIC, chemotherapy and supportive treatment, the patient successfully recovered from DIC and achieved complete remission after induction therapy. He achieved long-term survival via subsequent hematopoietic stem cell transplantation. Conclusion: Non-APL patients with DIC are critically severe and early identification and timely intervention are necessary for them.