[Acute promyelocytic leukemia with disseminated intravascular coagulation: a case report and literature review].

Acute promyelocytic leukemia (APL) is characterized by an aggressive onset and rapid progression. During induction chemotherapy, it is prone to being complicated by disseminated intravascular coagulation (DIC), which is a leading cause of early death in patients. This study reports a case of APL complicated by DIC during induction therapy with all-trans retinoic acid (ATRA) combined with arsenic trioxide (ATO). The patient's coagulopathy was corrected through active transfusion of blood products and replacement therapy with coagulation factors. Subsequently, complete remission was achieved after multiple courses of chemotherapy. This article provides a detailed description of the patient's disease onset and treatment process, exploring the differences in pathogenesis, clinical presentation, and treatment strategies between APL-associated DIC and DIC caused by other diseases, alongside a review of the relevant literature.