急性B型主动脉夹层诊断与治疗的问题与确定性。

IF 1.9 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Reviews in cardiovascular medicine Pub Date : 2025-02-20 eCollection Date: 2025-02-01 DOI:10.31083/RCM26807
Luigi Lovato, Maria Adriana Cocozza, Alessandro Onori, Rossella Fattori
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引用次数: 0

摘要

B型主动脉夹层(TBAD)是一种严重的心血管疾病,需要及时诊断和干预,以防止危及生命的并发症。本综述的目的是集中在当代TBAD管理中最关键和最具争议的方面。人们认识到,在急性期,计算机断层血管造影(CTA)在评估剥离程度和监测疾病进展方面发挥着重要作用。CTA通过提供主动脉解剖和动态血流变化的详细评估,显著改善了TBAD的管理,使其成为识别可能需要早期干预的急性高危患者的基石成像方式。最近,磁共振成像(MRI)和正电子发射断层扫描(PET)技术的新进展有可能提供进一步的信息,而不仅仅是成像。然而,这种复杂的技术应该保留给急性期后病情稳定的患者。经过几十年的药物治疗和高风险手术,胸血管内主动脉修复术(TEVAR)已成为复杂TBAD的微创替代手术,具有较低的围手术期发病率和死亡率。然而,它在简单的TBAD中的使用仍然是一个持续争论的话题。虽然最近的研究表明,先发制人的TEVAR联合最佳药物治疗可以减少晚期不良事件并改善长期预后,但这些发现仍存在争议。这篇综述批判性地分析了目前关于TEVAR诊断和治疗的文献,在临床实践的背景下评估这些争议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Questions and Certainty in Diagnosis and Management of Acute Type B Aortic Dissection.

Type B aortic dissection (TBAD) is a severe cardiovascular condition that requires timely diagnosis and intervention to prevent life-threatening complications. The aim of this review was to focus on the most crucial and controversial aspects of contemporary TBAD management. It is recognized that in the acute phase, computed tomography angiography (CTA) plays an essential role in evaluating the extent of the dissection and monitoring disease progression. CTA has significantly improved the management of TBAD by providing detailed assessments of aortic anatomy and dynamic flow changes, positioning it as the cornerstone imaging modality for identifying acute high-risk patients who may require early intervention. Recently, new advances in magnetic resonance imaging (MRI) and positron emission tomography (PET) technology have the potential to provide further information beyond imaging alone. However, such sophisticated techniques should be reserved for stable patients after the acute phase. After decades of medical therapy and high risk surgery, thoracic endovascular aortic repair (TEVAR) has emerged as a minimally invasive alternative to open surgery for complicated TBAD, offering lower perioperative morbidity and mortality. Nevertheless, its use in uncomplicated TBAD remains a topic of ongoing debate. While recent studies suggest that preemptive TEVAR combined with optimal medical therapy may reduce late adverse events and improve long-term outcomes, these findings remain controversial. This review critically analyzes the current literature on both diagnosis and TEVAR treatment, evaluating these controversies in the context of clinical practice.

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来源期刊
Reviews in cardiovascular medicine
Reviews in cardiovascular medicine 医学-心血管系统
CiteScore
2.70
自引率
3.70%
发文量
377
审稿时长
1 months
期刊介绍: RCM is an international, peer-reviewed, open access journal. RCM publishes research articles, review papers and short communications on cardiovascular medicine as well as research on cardiovascular disease. We aim to provide a forum for publishing papers which explore the pathogenesis and promote the progression of cardiac and vascular diseases. We also seek to establish an interdisciplinary platform, focusing on translational issues, to facilitate the advancement of research, clinical treatment and diagnostic procedures. Heart surgery, cardiovascular imaging, risk factors and various clinical cardiac & vascular research will be considered.
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