弓形虫病预防实践：国际儿童实体器官移植中心的调查。

IF 1.4 4区医学 Q3 PEDIATRICS

Pediatric Transplantation Pub Date : 2025-05-01 DOI:10.1111/petr.70058

Benjamin R Hanisch, Monica I Ardura, Inci Yildirim, Mignon McCulloch, Marian G Michaels, Anita Verma

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引用次数: 0

摘要

背景：刚地弓形虫可在器官移植后引起机会性感染，导致危及生命的播散性疾病。然而，缺乏儿科特异性数据来指导实体器官移植后预防弓形虫病的建议。方法：为了评估目前的做法，对国际儿科移植提供者进行了调查。结果：不同中心和器官类型的筛查和预防策略存在相当大的差异，心脏移植项目进行了更多的筛查和预防。甲氧苄啶/磺胺甲恶唑是各移植物首选的预防药物；在患者接受预防治疗期间，未召回弓形虫病病例。结论：弓形虫病的最佳预防策略尚需进一步研究和规范。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Toxoplasmosis Prophylaxis Practices: A Survey of International Pediatric Solid Organ Transplantation Centers.

Background: Toxoplasma gondii can cause opportunistic infections leading to life-threatening disseminated disease after organ transplantation. However, there is a paucity of pediatric-specific data to guide recommendations for the prevention of toxoplasmosis after solid organ transplantation.

Methods: To assess current practices, international pediatric transplant providers were surveyed.

Results: Considerable variability in both screening and prophylaxis strategies was found across centers and organ types, with heart transplant programs performing more screening and prophylaxis. Trimethoprim/sulfamethoxazole was the preferred prophylaxis agent for each graft; no toxoplasmosis cases were recalled while patients received prophylaxis.

Conclusion: More research is needed to clarify and standardize the optimal toxoplasmosis prevention strategy.

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来源期刊

Pediatric Transplantation 医学-小儿科

CiteScore

2.90

自引率

15.40%

发文量

216

审稿时长

3-8 weeks

期刊介绍： The aim of Pediatric Transplantation is to publish original articles of the highest quality on clinical experience and basic research in transplantation of tissues and solid organs in infants, children and adolescents. The journal seeks to disseminate the latest information widely to all individuals involved in kidney, liver, heart, lung, intestine and stem cell (bone-marrow) transplantation. In addition, the journal publishes focused reviews on topics relevant to pediatric transplantation as well as timely editorial comment on controversial issues.