Recurrent Idiopathic Methicillin-sensitive Staphylococcus aureus Pericarditis in a Patient with SARS-CoV-2 Infection and Septic Bacteremia: Case Report.

Purulent pericarditis (PPc) is a rare but clinically significant form of pericarditis that is typically associated with severe infection. Diagnosis is made by aspirating purulent fluid from the pericardial space, although cultures or gram stains of this fluid often yield negative results. Early detection and treatment are important in preventing severe complications such as cardiac tamponade, persistent infection, and the need for advanced therapies. This report describes the case of a 56-year-old man with multiple comorbidities, including diabetic ketoacidosis, COVID-19, and methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia, who was diagnosed with PPc after developing early cardiac tamponade and undergoing successful pericardiocentesis.