基于动量调频网络的低剂量计算机断层扫描重建

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Qixiang Sun , Ning He , Ping Yang , Xing Zhao
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引用次数: 0

摘要

背景与目的:近年来对低剂量计算机断层扫描(LDCT)重建方法的研究将基于模型的数据驱动(MBDD)方法带到了最前沿。MBDD中一个突出的架构需要基于模型的迭代重建(MBIR)与深度学习(DL)的集成。虽然这种方法提供了利用来自正弦图和图像域的信息的优势,但它也暴露了一些不足。首先,深度学习方法在MBDD领域的有效性需要细致的增强,因为它直接影响计算成本和重建图像的质量。其次,高计算成本和大量迭代限制了MBDD方法的开发。最后但并非最不重要的是,CT重建对像素精度很敏感,而DL方法中损失函数的作用对于满足这一要求至关重要。方法:本文通过三个主要贡献来推进MBDD方法。首先,我们引入了一种创新的频率调整网络(FAN),可以在推理阶段有效地调整高频和低频分量,从而大大提高重构性能。其次,我们开发了基于动量的频率调整网络(MFAN),它利用动量项作为外推策略,以促进在连续迭代中扩大变化,最终形成快速收敛框架。最后,我们深入研究了CT图像的视觉特性,并提出了一种独特的损失函数,称为焦细节损失(Focal Detail loss, FDL)。FDL功能在整个训练阶段保留了精细的细节,显著提高了重建质量。结果:通过在AAPM-Mayo公共数据集和真实仔猪数据集上的一系列实验验证,上述三种贡献均表现出优异的性能。作为一种迭代方法,MFAN在10次迭代中实现了收敛,比其他方法更快。消融研究进一步突出了各贡献的先进性能。结论:本文提出了一种基于mbdd的LDCT重建方法,该方法采用带焦点细节损失函数的动量调频网络。这种方法大大减少了收敛所需的迭代次数,同时在视觉和数值分析中获得了更好的重建结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Low dose computed tomography reconstruction with momentum-based frequency adjustment network

Low dose computed tomography reconstruction with momentum-based frequency adjustment network

Background and Objective:

Recent investigations into Low-Dose Computed Tomography (LDCT) reconstruction methods have brought Model-Based Data-Driven (MBDD) approaches to the forefront. One prominent architecture within MBDD entails the integration of Model-Based Iterative Reconstruction (MBIR) with Deep Learning (DL). While this approach offers the advantage of harnessing information from sinogram and image domains, it also reveals several deficiencies. First and foremost, the efficacy of DL methods within the realm of MBDD necessitates meticulous enhancement, as it directly impacts the computational cost and the quality of reconstructed images. Next, high computational costs and a high number of iterations limit the development of MBDD methods. Last but not least, CT reconstruction is sensitive to pixel accuracy, and the role of loss functions within DL methods is crucial for meeting this requirement.

Methods:

This paper advances MBDD methods through three principal contributions. Firstly, we introduce an innovative Frequency Adjustment Network (FAN) that effectively adjusts both high and low-frequency components during the inference phase, resulting in substantial enhancements in reconstruction performance. Second, we develop the Momentum-based Frequency Adjustment Network (MFAN), which leverages momentum terms as an extrapolation strategy to facilitate the amplification of changes throughout successive iterations, culminating in a rapid convergence framework. Lastly, we delve into the visual properties of CT images and present a unique loss function named Focal Detail Loss (FDL). The FDL function preserves fine details throughout the training phase, significantly improving reconstruction quality.

Results:

Through a series of experiments validation on the AAPM-Mayo public dataset and real-world piglet datasets, the aforementioned three contributions demonstrated superior performance. MFAN achieved convergence in 10 iterations as an iteration method, faster than other methods. Ablation studies further highlight the advanced performance of each contribution.

Conclusions:

This paper presents an MBDD-based LDCT reconstruction method using a momentum-based frequency adjustment network with a focal detail loss function. This approach significantly reduces the number of iterations required for convergence while achieving superior reconstruction results in visual and numerical analyses.
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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