经静脉栓塞治疗脑动静脉畸形。

Journal of neuroendovascular therapy Pub Date : 2025-01-01 Epub Date: 2024-07-01 DOI:10.5797/jnet.ra.2024-0035
Masaomi Koyanagi, Masanori Goto, Junichi Takeda, Ryu Fukumitsu, Tadashi Sunohara, Nobuyuki Fukui, Yuki Takano, Kunimasa Teranishi, Chiaki Sakai, Nobuyuki Sakai, Tsuyoshi Ohta
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引用次数: 0

摘要

脑动静脉畸形(bAVMs)是一种罕见的血管病变,在年轻人中发现,表现出多种临床表现,从无症状到自发性颅内出血、癫痫发作或头痛。尽管血管内工具和方法有所改进,但单独经动脉栓塞的成功率很少超过50%,即使使用乙烯乙烯醇共聚物也是如此。经静脉栓塞(TVE)是一种很有前途的选择,特别是对于位于远端或无法通过动脉途径进入的bavm。尽管有可能实现高血管造影治愈率,但对出血并发症的担忧仍然存在,限制了其采用。这篇综述文章概述了TVE的适应症和方法,讨论了并发症,并强调了安全执行TVE所需的基本专业知识以及减轻相关风险的策略。临床结果显示,尽管仍存在挑战,特别是在设备可及性和风险管理方面,但在闭塞率和良好的神经学结果方面,有希望的结果。尽管存在这些挑战,TVE仍然是治疗bavm的一种有价值的替代方法,特别是对于对手术干预有抵抗力的病例,强调了仔细选择患者和手术专业知识的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transvenous Embolization for Brain Arteriovenous Malformations.

Brain arteriovenous malformations (bAVMs) are uncommon vascular lesions found in young individuals exhibiting diverse clinical manifestations ranging from asymptomatic to spontaneous intracranial hemorrhage, seizures, or headaches. Despite improvements in endovascular tools and methods, standalone transarterial embolization seldom achieves success rates surpassing 50%, even when employing ethylene vinyl alcohol copolymers. Transvenous embolization (TVE) emerges as a promising option, especially for bAVMs situated distally or inaccessible through arterial routes. Despite the possibility of achieving high angiographic cure rates, concerns regarding hemorrhagic complications persist, limiting its adoption. This review article outlines the indications and methodology of TVE, discusses complications, and highlights the essential expertise needed for the safe execution of TVE along with strategies to mitigate associated risks. Clinical results reveal promising outcomes in terms of obliteration rates and favorable neurological results, although challenges persist, particularly regarding device accessibility and risk management. Despite these challenges, TVE remains a valuable alternative for managing bAVMs, particularly for cases resistant to surgical intervention, emphasizing the significance of careful patient selection and procedural expertise.

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