{"title":"印度海得拉巴当地市场常见草药中的重金属污染及相关健康风险。","authors":"Vakdevi Validandi, Srinivasu Kurella, Sumitra Gorain, Yamuna Sagubandi, Ajantha Rudhra, Sri Kavya Deepika Annamanedi, Naveen Kumar Ramachandrappa, Sukesh Narayan Sinha","doi":"10.1080/19393210.2025.2471065","DOIUrl":null,"url":null,"abstract":"<p><p>Heavy metal (HM) contamination in commonly consumed herbal medicines (<i>n</i> = 80), as determined by Liquid Chromatography-Inductively Coupled Plasma Mass Spectroscopy, revealed that 10% of the samples contained at least one HM which exceeded the maximum limits of the Ayurvedic Pharmacopoeia of India. The estimated daily intake of Cr was higher through the consumption of amla, brahmi, and lodhra bark, when compared to other HMs. The Hazard Quotient (1.8) and Hazard Index (2.3) exceeded 1 for brahmi consumption, suggesting potential non-carcinogenic health risks for the population. The Life Time Cancer Risk for brahmi was 2.95E-03, so above 10<sup>-4</sup>-10<sup>-6</sup>, which indicates a cancer risk to the population. Monte Carlo simulations for amla showed a skewed distribution, also suggesting its consumption to be a health risk. Therefore, proper management strategies and regular monitoring of herbal products are recommended to ensure the safety and efficacy of herbal medicines for the consumers.</p>","PeriodicalId":12286,"journal":{"name":"Food additives & contaminants. Part B, Surveillance","volume":" ","pages":"187-198"},"PeriodicalIF":2.5000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Heavy metal contamination in commonly consumed herbal medicines from local markets in Hyderabad, India, and associated health risks.\",\"authors\":\"Vakdevi Validandi, Srinivasu Kurella, Sumitra Gorain, Yamuna Sagubandi, Ajantha Rudhra, Sri Kavya Deepika Annamanedi, Naveen Kumar Ramachandrappa, Sukesh Narayan Sinha\",\"doi\":\"10.1080/19393210.2025.2471065\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Heavy metal (HM) contamination in commonly consumed herbal medicines (<i>n</i> = 80), as determined by Liquid Chromatography-Inductively Coupled Plasma Mass Spectroscopy, revealed that 10% of the samples contained at least one HM which exceeded the maximum limits of the Ayurvedic Pharmacopoeia of India. The estimated daily intake of Cr was higher through the consumption of amla, brahmi, and lodhra bark, when compared to other HMs. The Hazard Quotient (1.8) and Hazard Index (2.3) exceeded 1 for brahmi consumption, suggesting potential non-carcinogenic health risks for the population. The Life Time Cancer Risk for brahmi was 2.95E-03, so above 10<sup>-4</sup>-10<sup>-6</sup>, which indicates a cancer risk to the population. Monte Carlo simulations for amla showed a skewed distribution, also suggesting its consumption to be a health risk. Therefore, proper management strategies and regular monitoring of herbal products are recommended to ensure the safety and efficacy of herbal medicines for the consumers.</p>\",\"PeriodicalId\":12286,\"journal\":{\"name\":\"Food additives & contaminants. Part B, Surveillance\",\"volume\":\" \",\"pages\":\"187-198\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food additives & contaminants. Part B, Surveillance\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1080/19393210.2025.2471065\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food additives & contaminants. Part B, Surveillance","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1080/19393210.2025.2471065","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/26 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Heavy metal contamination in commonly consumed herbal medicines from local markets in Hyderabad, India, and associated health risks.
Heavy metal (HM) contamination in commonly consumed herbal medicines (n = 80), as determined by Liquid Chromatography-Inductively Coupled Plasma Mass Spectroscopy, revealed that 10% of the samples contained at least one HM which exceeded the maximum limits of the Ayurvedic Pharmacopoeia of India. The estimated daily intake of Cr was higher through the consumption of amla, brahmi, and lodhra bark, when compared to other HMs. The Hazard Quotient (1.8) and Hazard Index (2.3) exceeded 1 for brahmi consumption, suggesting potential non-carcinogenic health risks for the population. The Life Time Cancer Risk for brahmi was 2.95E-03, so above 10-4-10-6, which indicates a cancer risk to the population. Monte Carlo simulations for amla showed a skewed distribution, also suggesting its consumption to be a health risk. Therefore, proper management strategies and regular monitoring of herbal products are recommended to ensure the safety and efficacy of herbal medicines for the consumers.
期刊介绍：
Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling.
Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment.
The scope is initially restricted to:
Additives - food colours, artificial sweeteners, and preservatives;
Residues – veterinary drug and pesticide residues;
Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging.
Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet.
Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.
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