{"title":"Impact of Deep Learning 3D CT Super-Resolution on AI-Based Pulmonary Nodule Characterization.","authors":"Dongok Kim, Chulkyun Ahn, Jong Hyo Kim","doi":"10.3390/tomography11020013","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/objectives: </strong>Correct pulmonary nodule volumetry and categorization is paramount for accurate diagnosis in lung cancer screening programs. CT scanners with slice thicknesses of multiple millimetres are still common worldwide, and slice thickness has an adverse effect on the accuracy of the pulmonary nodule volumetry.</p><p><strong>Methods: </strong>We propose a deep learning based super-resolution technique to generate thin-slice CT images from thick-slice CT images. Analysis of the lung nodule volumetry and categorization accuracy was performed using commercially available AI-based lung cancer screening software.</p><p><strong>Results: </strong>The accuracy of pulmonary nodule categorization increased from 72.7 percent to 94.5 percent when thick-slice CT images were converted to generated-thin-slice CT images.</p><p><strong>Conclusions: </strong>Applying the super-resolution-based slice generation on thick-slice CT images prior to automatic nodule evaluation significantly increases the accuracy of pulmonary nodule volumetry and corresponding pulmonary nodule category.</p>","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"11 2","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11860810/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tomography","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/tomography11020013","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Impact of Deep Learning 3D CT Super-Resolution on AI-Based Pulmonary Nodule Characterization.
Background/objectives: Correct pulmonary nodule volumetry and categorization is paramount for accurate diagnosis in lung cancer screening programs. CT scanners with slice thicknesses of multiple millimetres are still common worldwide, and slice thickness has an adverse effect on the accuracy of the pulmonary nodule volumetry.
Methods: We propose a deep learning based super-resolution technique to generate thin-slice CT images from thick-slice CT images. Analysis of the lung nodule volumetry and categorization accuracy was performed using commercially available AI-based lung cancer screening software.
Results: The accuracy of pulmonary nodule categorization increased from 72.7 percent to 94.5 percent when thick-slice CT images were converted to generated-thin-slice CT images.
Conclusions: Applying the super-resolution-based slice generation on thick-slice CT images prior to automatic nodule evaluation significantly increases the accuracy of pulmonary nodule volumetry and corresponding pulmonary nodule category.
TomographyMedicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.70
自引率
10.50%
发文量
222
期刊介绍:
TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine.
Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians.
Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.