沙特阿拉伯北部地区婚前筛查项目中普通人群对遗传性血红蛋白病的认识和态度

IF 1.1 Q4 HEMATOLOGY
Mariah N Hafiz, Nida Suhail, Zakariya M S Mohammed, Husham O Elzein, Hibah A Almasmoum, Awad E Abass, Mohammed M Jawad, Saoussen Trabelsi
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引用次数: 0

摘要

背景:婚前筛查(PMS)是一个全国性的项目,帮助高危人群做出决定,避免遗传和性传播疾病传播给他们的配偶或未来的后代。本研究调查了沙特阿拉伯北部边境地区人民对经前综合症中遗传性血红蛋白病的认识和态度及其与各种社会人口因素的关系。方法:于2024年1月至3月在沙特阿拉伯北部地区进行横断面研究。通过问卷调查收集了478名18岁及以上的沙特参与者的数据。采用卡方检验确定分类变量之间的相关性。结果:所有受试者均熟悉经前症候群治疗方案。很大一部分参与者(79.3%)承认血缘关系会增加遗传性血液疾病的风险,而69.9%的人认为,如果父母双方都携带相同的遗传性血液疾病,他们的孩子可能会遗传这种疾病。高等教育程度、女性性别和年龄组别(30-40岁)是经前症候群知识的主要预测因素。大多数受访者(98.5%)对经前症候群是完成婚姻的先决条件持肯定态度。约82.8%的人表示,如果经前症候群结果不相符,他们将不会继续婚姻。结论:该研究表明,随着越来越多的人选择婚前筛查,一般人群对婚前筛查的认识和态度越来越积极。研究结果表明,经前综合症项目有助于做出明智的决策,因为伴侣不相容而选择放弃婚姻的参与者的增加就证明了这一点。该研究建议,考虑到年龄、教育程度和婚姻状况等人口因素,加强健康教育运动。此外,它提倡扩大经前症候群的范围,包括更广泛的健康和遗传疾病,以提高其整体功效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Awareness and Attitude of the General Population Towards Inherited Hemoglobinopathies in the Premarital Screening Program in the Northern Region of Saudi Arabia.

Background: Premarital screening (PMS) is a nationwide program that helps high-risk individuals make decisions to avoid genetic and sexually transmitted diseases from spreading to their spouse or future offspring. This study examined the knowledge and attitudes towards inherited hemoglobinopathies in PMS among the people of Northern Border Region in Saudi Arabia and their relationship to various sociodemographic factors. Methods: A cross-sectional study was undertaken in the Northern region of Saudi Arabia from January to March 2024. Data were gathered via questionnaire from 478 Saudi participants aged 18 years and older. The chi-square test was employed to determine the association between categorical variables. Results: All participants in the study were familiar with the PMS program. A significant portion of participants, 79.3%, acknowledged that consanguinity can increase the risk of hereditary blood disorders, while 69.9% believed that if both parents are carriers of the same genetic blood disease, their child may inherit it. Higher education, female gender, and age group (30-40) were found to be the main predictors of knowledge regarding PMS. Most of the participants (98.5%) had a positive attitude regarding the necessity of PMS as a prerequisite for marriage completion. About 82.8% indicated they would not continue with the marriage if the PMS results were incompatible. Conclusions: The study indicates a growing awareness and positive attitude towards premarital screening among the general population, with an increasing number of individuals opting for it. The findings suggest that PMS programs contribute to informed decision making, as evidenced by the rise in participants choosing to forgo marriage due to partner incompatibility. The study recommends the enhancement of health education campaigns by considering demographic factors such as age, education, and marital status. Additionally, it advocates for expanding the scope of PMS to include a wider range of health and genetic disorders to improve its overall efficacy.

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来源期刊
Hematology Reports
Hematology Reports HEMATOLOGY-
CiteScore
0.90
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0.00%
发文量
47
审稿时长
10 weeks
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