糖尿病患者急性冠脉综合征后低密度脂蛋白、胆固醇、血压和血糖的目标成就：来自中国心血管协会数据库- iHeart项目的发现。

IF 3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Global Heart Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI:10.5334/gh.1400

Jing Yang, Rui Zhang, Bing Han, Hui Li, Jingfeng Wang, Yihui Xiao, Xiaofan Yu, Shaofeng Guan, Cuilian Dai, Hua Yan, Tingbo Jiang, Hanbin Cui, Shuang Yang, Zeqi Zheng, Yugang Dong, Annai Wang, Guohai Su, Yan Wang

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引用次数: 0

摘要

目的：评价ACS合并糖尿病患者出院后12个月内代谢危险因素指标实现情况及影响因素。方法：我们回顾性分析来自中国心血管协会数据库- iheart项目的数据。纳入了2014年至2021年间诊断为ACS住院的患者，出院后12个月内至少有一次LDL-C、BP或HbA1c测量记录。我们进一步根据糖尿病状况对患者进行分层，并分析临床特征、测量策略与目标达成之间的相关性。结果：1027例（27.5%）符合条件的患者被诊断为糖尿病。糖尿病患者LDL-C、BP和HbA1c达标的比例分别为42.4%、61.5%和43.7%。然而，糖尿病患者的综合成功率明显低于非糖尿病患者（16.6% vs. 26.6%）。在3个月内进行第一次测量或在12个月内进行≥3次测量的糖尿病患者与实现联合目标呈正相关。结论：ACS患者多因素指标的实现并不理想，尤其是合并糖尿病的患者。最佳的出院后测量策略对于提高ACS患者代谢危险因素的综合管理至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Target Achievements of Low-Density Lipoprotein Cholesterol, Blood Pressure, and Glucose in Patients with Diabetes after Acute Coronary Syndrome: Findings from the Chinese Cardiovascular Association Database - iHeart Project.

Aim: To evaluate the achievement of metabolic risk factor targets and influencing factors in ACS patients with diabetes during the 12 months after discharge.

Methods: We retrospectively analyzed data from the Chinese Cardiovascular Association database-iHeart Project. Patients who were hospitalized with a diagnosis of ACS between 2014 and 2021 and who had at least one measurement record of LDL-C, BP, or HbA_1c within 12 months after discharge were included. We further stratified patients by diabetes status and analyzed the correlation between clinical characteristics, measurement strategy, and achievement of targets.

Results: Diabetes was identified in 1,027 (27.5%) of the eligible patients. The proportions of patients with diabetes achieving targets of LDL-C, BP, and HbA_1c levels were 42.4%, 61.5%, and 43.7%, respectively. However, combined achievement rate was significantly lower in patients with diabetes than patients without diabetes (16.6% vs. 26.6%). Patients with diabetes who underwent the first measurement within three months or had ≥3 measurements within 12 months were positively associated with achieving combined targets.

Conclusions: The achievement of multifactorial targets among patients with ACS is suboptimal, particularly among patients with concomitant diabetes. The optimal measurement strategy post-discharge is essential for improving the comprehensive management of metabolic risk factors in ACS patients.

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来源期刊

Global Heart Medicine-Cardiology and Cardiovascular Medicine

CiteScore

5.70

自引率

5.40%

发文量

审稿时长

5 weeks

期刊介绍： Global Heart offers a forum for dialogue and education on research, developments, trends, solutions and public health programs related to the prevention and control of cardiovascular diseases (CVDs) worldwide, with a special focus on low- and middle-income countries (LMICs). Manuscripts should address not only the extent or epidemiology of the problem, but also describe interventions to effectively control and prevent CVDs and the underlying factors. The emphasis should be on approaches applicable in settings with limited resources. Economic evaluations of successful interventions are particularly welcome. We will also consider negative findings if important. While reports of hospital or clinic-based treatments are not excluded, particularly if they have broad implications for cost-effective disease control or prevention, we give priority to papers addressing community-based activities. We encourage submissions on cardiovascular surveillance and health policies, professional education, ethical issues and technological innovations related to prevention. Global Heart is particularly interested in publishing data from updated national or regional demographic health surveys, World Health Organization or Global Burden of Disease data, large clinical disease databases or registries. Systematic reviews or meta-analyses on globally relevant topics are welcome. We will also consider clinical research that has special relevance to LMICs, e.g. using validated instruments to assess health-related quality-of-life in patients from LMICs, innovative diagnostic-therapeutic applications, real-world effectiveness clinical trials, research methods (innovative methodologic papers, with emphasis on low-cost research methods or novel application of methods in low resource settings), and papers pertaining to cardiovascular health promotion and policy (quantitative evaluation of health programs.