用两种方法测定磁场输出校正系数的两个探测器在中心轴。

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Stephan Frick, Moritz Schneider, Daniela Thorwarth, Ralf-Peter Kapsch
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引用次数: 0

摘要

目的:调试一个MR-linac处理计划系统需要输出校正因子kB, qcline,以便检测器准确测量不同场尺寸下的直线加速器输出。在本研究中,kB, qclini在中轴线上使用两种方法进行测定:一种方法是将磁场影响的校正与小磁场的校正结合在一个因素中(kB, qclini),另一种方法是隔离磁场的影响,允许使用文献中没有磁场的输出校正因子kqclini来测定kB, qclini。 ;为了确定kB, qclint并检查其在不同光子能量和磁通量密度下的行为在小场中,使用电离室(0.07 cm³敏感体积)和固态探测器在实验设施上对两种方法进行了测量。通过蒙特卡罗模拟确定了吸收剂量随场大小的变化。为了评估临床适用性,在1.5 T MR-linac上进行了额外的测量。 ;主要结果: ;当磁场大小为bbb3 × 3cm2, brbrt为-1.5 ~ 1.5 T,光子能量为6 ~ 8mv时,kqclina没有随磁场变化而变化。与1.5 T MR-linac的测量结果比较证实了这一点。对于≤3 × 3 cm2, kB, qclin依赖于光子能量和b。对于1.5 T和6 MV,电离室的kqclini高达3%,固态检测器的kqclini高达7%。意义: ;kB, qclini成功地测定了两个检测器,使其能够在1.5 T MR-linac上使用。对于bbbb3 × 3cm2的场大小,kB, qclini是适用于所有可用的垂直MR-linac系统的小场剂量测定的大多数探测器之一,如文献所证实。对于这些场大小和探测器,考虑剂量计在参考场中由于磁场引起的响应变化的校正因子kB,Q可用于交叉校准。因此,未来的研究可能只关注小范围的领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Determination of output correction factors in magnetic fields using two methods for two detectors at the central axis.

Objective.Commissioning an MR-linac treatment planning system requires output correction factors,kB→,Qclin,Qmsrfclin,fmsr, for detectors to accurately measure the linac's output at various field sizes. In this study,kB→,Qclin,Qmsrfclin,fmsrwas determined at the central axis using two methods: one that combines the corrections for the influence of the magnetic field and the small field in a single factor (kB→,Qclin,Qmsrfclin,fmsr), and a second that isolates the magnetic field's influence, allowing the use of output correction factors without a magnetic field,kQclin,Qmsrfclin,fmsr, from literature for determiningkB→,Qclin,Qmsrfclin,fmsr.Approach.To determinekB→,Qclin,Qmsrfclin,fmsrand examine its behaviour across different photon energies and magnetic flux densitiesBin small fields, measurements with an ionization chamber (0.07 cm3sensitive volume) and a solid-state detector were carried out at an experimental facility for both approaches. Changes in absorbed dose to water with field size were determined via Monte Carlo simulations. To evaluate clinical applicability, additional measurements were conducted on a 1.5 T MR-linac.Main results.Both methods determined comparablekB→,Qclin,Qmsrfclin,fmsrresults. For field sizes >3 × 3 cm2,Branging from -1.5 to 1.5 T and photon energies of 6 and 8 MV, no change ofkQclin,Qmsrfclin,fmsras a function of the magnetic field was observed. Comparison with measurement results from the 1.5 T MR-linac confirm this. For ⩽3 × 3 cm2,kB→,Qclin,Qmsrfclin,fmsrdepends on photon energy andB. For 1.5 T and 6 MV,BreduceskQclin,Qmsrfclin,fmsrup to 3% for the ionization chamber and up to 7% for the solid-state detector.Significance.kB→,Qclin,Qmsrfclin,fmsrwere successfully determined for two detectors, enabling their use at a 1.5 T MR-linac. For field sizes of >3 × 3 cm2,kB→,Qclin,Qmsrfclin,fmsris one for most detectors suitable for small field dosimetry for all available perpendicular MR-linac systems, as confirmed in the literature. For these field sizes and detectors, the correction factor accounting for the dosimeter response change in the reference field due to the magnetic field,kB→,Qmsrfmsr, can be used for cross-calibration. Therefore, future research may only focus on small field sizes.

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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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