通过扫描和光学探针纳米层析技术分析生物材料和物体的三维纳米结构

IF 0.3 4区物理与天体物理 Q4 PHYSICS, NUCLEAR

Physics of Atomic Nuclei Pub Date : 2025-02-22 DOI:10.1134/S1063778824100107

A. E. Efimov, O. I. Agapova, I. I. Agapov

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摘要

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Analyzing 3D Nanostructures of Biological Materials and Objects via Scanning- and Optical-Probe Nanotomography

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Analyzing 3D Nanostructures of Biological Materials and Objects via Scanning- and Optical-Probe Nanotomography

The authors consider current ways of studying the 3D nanostructure of biomaterials and biological objects based on scanning probe nanotomography—a combination of fluorescence microscopy, probe microscopy, and ultramicrotomy. Results are presented from experiments to study the 3D nanostructure of composite scaffolds based on Bombyx mori silk fibroin and microparticles of an extracellular matrix obtained from decellularized liver tissue. Such scaffolds have great potential for using in regenerative medicine. It is shown that probe nanotomography allows effective analysis of the 3D nanostructure of microinclusions and their morphological parameters that influence the biological activity of products.

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来源期刊

Physics of Atomic Nuclei 物理-物理：核物理

CiteScore

0.60

自引率

25.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Physics of Atomic Nuclei is a journal that covers experimental and theoretical studies of nuclear physics: nuclear structure, spectra, and properties; radiation, fission, and nuclear reactions induced by photons, leptons, hadrons, and nuclei; fundamental interactions and symmetries; hadrons (with light, strange, charm, and bottom quarks); particle collisions at high and superhigh energies; gauge and unified quantum field theories, quark models, supersymmetry and supergravity, astrophysics and cosmology.