超越致幻剂:一般精神病学实践中的设置和设置。

IF 3.7 4区 医学 Q1 PSYCHIATRY
International Review of Psychiatry Pub Date : 2024-12-01 Epub Date: 2024-11-13 DOI:10.1080/09540261.2024.2419662
Zofia Kozak, Christopher W T Miller
{"title":"超越致幻剂:一般精神病学实践中的设置和设置。","authors":"Zofia Kozak, Christopher W T Miller","doi":"10.1080/09540261.2024.2419662","DOIUrl":null,"url":null,"abstract":"<p><p>Psychedelic compounds continue gaining scientific and regulatory traction as potential new treatments for psychiatric disorders. While most psychiatrists will likely not work directly with these compounds, psychedelic research practices provide insights that may improve conventional psychiatric care. Through its emphasis on 'set and setting' (mindset and environment, respectively), psychedelic research highlights the importance of non-pharmacologic factors maximizing therapeutic outcomes. While psychedelics and serotonergic antidepressants are distinctly different in their subjective experience, new findings suggest mechanistic overlap between them. Both have been found to modulate neurotrophins, enhance neuroplasticity, and reopen critical periods of learning, molded by the environmental context in which they are administered.</p><p><p>This paper will argue that by integrating insights from psychedelic research (particularly set and setting), depression treatment outcomes in traditional psychiatric settings can improve by optimizing non-pharmacological factors in treatment, including the provision of high-quality psychotherapy.</p>","PeriodicalId":51391,"journal":{"name":"International Review of Psychiatry","volume":"36 8","pages":"833-840"},"PeriodicalIF":3.7000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Beyond psychedelics: set and setting in general psychiatric practice.\",\"authors\":\"Zofia Kozak, Christopher W T Miller\",\"doi\":\"10.1080/09540261.2024.2419662\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Psychedelic compounds continue gaining scientific and regulatory traction as potential new treatments for psychiatric disorders. While most psychiatrists will likely not work directly with these compounds, psychedelic research practices provide insights that may improve conventional psychiatric care. Through its emphasis on 'set and setting' (mindset and environment, respectively), psychedelic research highlights the importance of non-pharmacologic factors maximizing therapeutic outcomes. While psychedelics and serotonergic antidepressants are distinctly different in their subjective experience, new findings suggest mechanistic overlap between them. Both have been found to modulate neurotrophins, enhance neuroplasticity, and reopen critical periods of learning, molded by the environmental context in which they are administered.</p><p><p>This paper will argue that by integrating insights from psychedelic research (particularly set and setting), depression treatment outcomes in traditional psychiatric settings can improve by optimizing non-pharmacological factors in treatment, including the provision of high-quality psychotherapy.</p>\",\"PeriodicalId\":51391,\"journal\":{\"name\":\"International Review of Psychiatry\",\"volume\":\"36 8\",\"pages\":\"833-840\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Review of Psychiatry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/09540261.2024.2419662\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/13 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Review of Psychiatry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09540261.2024.2419662","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/13 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0

摘要

迷幻化合物作为治疗精神疾病的潜在新疗法,不断获得科学和监管方面的关注。虽然大多数精神病学家可能不会直接使用这些化合物,但迷幻药的研究实践提供了可能改善传统精神病学护理的见解。通过强调“设定和设定”(分别是心态和环境),迷幻药研究强调了非药物因素最大化治疗结果的重要性。虽然致幻剂和5 -羟色胺类抗抑郁药在主观体验上明显不同,但新的发现表明它们之间存在机制上的重叠。研究发现,这两种药物都可以调节神经营养物质,增强神经可塑性,并重新开启学习的关键时期,这是由它们所处的环境背景所塑造的。本文认为,通过整合迷幻药研究的见解(特别是设置和设置),传统精神病学环境中的抑郁症治疗结果可以通过优化治疗中的非药物因素来改善,包括提供高质量的心理治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Beyond psychedelics: set and setting in general psychiatric practice.

Psychedelic compounds continue gaining scientific and regulatory traction as potential new treatments for psychiatric disorders. While most psychiatrists will likely not work directly with these compounds, psychedelic research practices provide insights that may improve conventional psychiatric care. Through its emphasis on 'set and setting' (mindset and environment, respectively), psychedelic research highlights the importance of non-pharmacologic factors maximizing therapeutic outcomes. While psychedelics and serotonergic antidepressants are distinctly different in their subjective experience, new findings suggest mechanistic overlap between them. Both have been found to modulate neurotrophins, enhance neuroplasticity, and reopen critical periods of learning, molded by the environmental context in which they are administered.

This paper will argue that by integrating insights from psychedelic research (particularly set and setting), depression treatment outcomes in traditional psychiatric settings can improve by optimizing non-pharmacological factors in treatment, including the provision of high-quality psychotherapy.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
5.10
自引率
0.00%
发文量
85
期刊介绍: The International Review of Psychiatry is the premier review journal in the field with a truly international authorship and readership. Each bimonthly issue is dedicated to a specific theme relevant to psychiatry, edited by recognized experts on the topic, who are selected by the Editors and the Editorial Board. Each issue provides in-depth, scholarly reviews of the topic in focus. The Journal reaches a broad international readership including clinicians, academics, educators, and researchers who wish to remain up-to-date with recent and rapid developments in various fields of psychiatry. It aims to be of value to trainees by choosing topics of relevance to career development, which are also suitable for clinicians for continuing professional development.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信