利用多束干涉进行深手术深度的无创激光手术。

IF 1.3 Q4 ENGINEERING, BIOMEDICAL
Medical Devices-Evidence and Research Pub Date : 2025-02-15 eCollection Date: 2025-01-01 DOI:10.2147/MDER.S498706
Joyce Liu
{"title":"利用多束干涉进行深手术深度的无创激光手术。","authors":"Joyce Liu","doi":"10.2147/MDER.S498706","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Laser surgery can use photo-chemical, photo-thermal, photo-ablative, and photo-mechanical effects to treat various tissues in the human body, and has unique advantages of extremely high precision, non-invasive penetration, and fast operation speed. However, at present, the effective penetration depth of directly illuminating light in the body is only several millimeters. Therefore, increasing the safe operating depth for non-invasive laser surgery will have important, widespread, and irreplaceable applications in the future.</p><p><strong>Methods: </strong>The method is based on improving a recently emerged technique. Its principle involves using a negative dispersion device to broaden the width of the short light pulse first. Then, after the pulse enters the body, as its peak intensity is reduced, the skin and healthy tissues in the laser propagation path cannot be injured. Meanwhile, since body tissues have positive dispersion, the broadened width of the laser pulse will be shortened back. When the broadened pulse is completely shortened, a thin inner light layer with high intensity will be formed in the body and used as a scalpel to treat target tissue.</p><p><strong>Results: </strong>The theoretical calculation results have shown that the designed apparatus has excellent performance. Its safe non-invasive operating depth can be more than 70 millimeters with the possibility of up to 130 millimeters. Surgery precisions are around 1 micron transversely and about 1 millimeter longitudinally in theory.</p><p><strong>Conclusion: </strong>An improved method of non-invasive laser surgery with deep operation depth has been investigated theoretically. The calculations show that the designed apparatus has excellent performance. The proposed method depends on two well-known physical phenomena: light pulse broadening and shortening caused by optical negative and positive dispersions, and thus has solid basis. The developed method will have important, widespread and irreplaceable applications in the medical surgery field.</p>","PeriodicalId":47140,"journal":{"name":"Medical Devices-Evidence and Research","volume":"18 ","pages":"123-136"},"PeriodicalIF":1.3000,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840436/pdf/","citationCount":"0","resultStr":"{\"title\":\"Non-Invasive Laser Surgery With Deep Operating Depth Using Multibeam Interference.\",\"authors\":\"Joyce Liu\",\"doi\":\"10.2147/MDER.S498706\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Laser surgery can use photo-chemical, photo-thermal, photo-ablative, and photo-mechanical effects to treat various tissues in the human body, and has unique advantages of extremely high precision, non-invasive penetration, and fast operation speed. However, at present, the effective penetration depth of directly illuminating light in the body is only several millimeters. Therefore, increasing the safe operating depth for non-invasive laser surgery will have important, widespread, and irreplaceable applications in the future.</p><p><strong>Methods: </strong>The method is based on improving a recently emerged technique. Its principle involves using a negative dispersion device to broaden the width of the short light pulse first. Then, after the pulse enters the body, as its peak intensity is reduced, the skin and healthy tissues in the laser propagation path cannot be injured. Meanwhile, since body tissues have positive dispersion, the broadened width of the laser pulse will be shortened back. When the broadened pulse is completely shortened, a thin inner light layer with high intensity will be formed in the body and used as a scalpel to treat target tissue.</p><p><strong>Results: </strong>The theoretical calculation results have shown that the designed apparatus has excellent performance. Its safe non-invasive operating depth can be more than 70 millimeters with the possibility of up to 130 millimeters. Surgery precisions are around 1 micron transversely and about 1 millimeter longitudinally in theory.</p><p><strong>Conclusion: </strong>An improved method of non-invasive laser surgery with deep operation depth has been investigated theoretically. The calculations show that the designed apparatus has excellent performance. The proposed method depends on two well-known physical phenomena: light pulse broadening and shortening caused by optical negative and positive dispersions, and thus has solid basis. The developed method will have important, widespread and irreplaceable applications in the medical surgery field.</p>\",\"PeriodicalId\":47140,\"journal\":{\"name\":\"Medical Devices-Evidence and Research\",\"volume\":\"18 \",\"pages\":\"123-136\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-02-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840436/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Devices-Evidence and Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/MDER.S498706\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Devices-Evidence and Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/MDER.S498706","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

摘要

目的:激光手术可以利用光化学、光热、光烧蚀、光力学等效应对人体各种组织进行治疗,具有极高的精度、无创穿透、手术速度快等独特优点。但目前,直射光在人体的有效穿透深度只有几毫米。因此,增加无创激光手术的安全操作深度将在未来具有重要、广泛和不可替代的应用。方法:该方法是基于改进一种新出现的技术。它的原理包括使用负色散装置首先拓宽短光脉冲的宽度。然后,脉冲进入人体后,由于其峰值强度降低,在激光传播路径中的皮肤和健康组织不会受到伤害。同时,由于人体组织具有正色散,激光脉冲的宽度将被缩短回来。当加宽的脉冲完全缩短后,体内会形成一层薄而强度高的内光层,用作治疗目标组织的手术刀。结果:理论计算结果表明,所设计的装置具有优良的性能。其安全的非侵入性操作深度可超过70毫米,最高可达130毫米。理论上,手术的横向精度约为1微米,纵向精度约为1毫米。结论:从理论上探讨了一种改进的手术深度较深的无创激光手术方法。计算表明,所设计的装置具有优良的性能。该方法依赖于光的负色散和正色散引起的光脉冲加宽和缩短这两种众所周知的物理现象,因此具有坚实的基础。该方法将在外科医学领域具有重要、广泛和不可替代的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-Invasive Laser Surgery With Deep Operating Depth Using Multibeam Interference.

Purpose: Laser surgery can use photo-chemical, photo-thermal, photo-ablative, and photo-mechanical effects to treat various tissues in the human body, and has unique advantages of extremely high precision, non-invasive penetration, and fast operation speed. However, at present, the effective penetration depth of directly illuminating light in the body is only several millimeters. Therefore, increasing the safe operating depth for non-invasive laser surgery will have important, widespread, and irreplaceable applications in the future.

Methods: The method is based on improving a recently emerged technique. Its principle involves using a negative dispersion device to broaden the width of the short light pulse first. Then, after the pulse enters the body, as its peak intensity is reduced, the skin and healthy tissues in the laser propagation path cannot be injured. Meanwhile, since body tissues have positive dispersion, the broadened width of the laser pulse will be shortened back. When the broadened pulse is completely shortened, a thin inner light layer with high intensity will be formed in the body and used as a scalpel to treat target tissue.

Results: The theoretical calculation results have shown that the designed apparatus has excellent performance. Its safe non-invasive operating depth can be more than 70 millimeters with the possibility of up to 130 millimeters. Surgery precisions are around 1 micron transversely and about 1 millimeter longitudinally in theory.

Conclusion: An improved method of non-invasive laser surgery with deep operation depth has been investigated theoretically. The calculations show that the designed apparatus has excellent performance. The proposed method depends on two well-known physical phenomena: light pulse broadening and shortening caused by optical negative and positive dispersions, and thus has solid basis. The developed method will have important, widespread and irreplaceable applications in the medical surgery field.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Medical Devices-Evidence and Research
Medical Devices-Evidence and Research ENGINEERING, BIOMEDICAL-
CiteScore
2.80
自引率
0.00%
发文量
41
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信