{"title":"腹股沟下深静脉血栓患者左中、重度髂总静脉受压与累及髂静脉血栓形成的关系","authors":"Maofeng Gong, Rui Jiang, Xu He, Zhengcan Wu, Jianping Gu","doi":"10.1007/s00270-025-03971-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the association between the degree of common iliac vein (CIV) compression and the incidence of iliac vein involvement thrombosis (IVT) in patients with infrainguinal deep vein thrombosis (DVT).</p><p><strong>Methods: </strong>This was a single center retrospective study. Between January 2015 and July 2023, infrainguinal DVT patients with or without IVT were included. Patient baseline demographics, clinical characteristics, and radiographic variables were collected and analyzed. Univariate analysis followed by multivariate analysis was used for IVT to determine odds ratio (OR) with a 95% confidence interval (CI). The association of the degree of CIV compression and IVT was evaluated by restricted cubic spines (RCS) on a continuous scale.</p><p><strong>Results: </strong>222 left-sided DVT patients [140 (63.1%) patients diagnosed with IVT, and 82 (36.9%) without] were included. Univariate analyses revealed a higher prevalence of female gender (55.7 vs. 41.5%, p = .040) and CIV compression among patients with left-sided IVT compared to those without IVT. After adjusting for female gender, a strong positive association between IVT and moderate (compression degree > 50% and ≤ 75%) (adjusted OR 3.75; 95% CI 1.571-8.974; p = .003) to severe (> 75%) (adjusted OR 4.05; 95% CI 1.615-10.134; p = .003) CIV compression degrees remained, indicating moderate or severe compression significantly increased IVT risk. RCS showed that a greater CIV minimum diameter or a smaller compression percentage was negatively associated with IVT incidence at a CIV minimum diameter was > 4.1 mm (p < .001) or compression percentage was < 61.0% (p < .001).</p><p><strong>Conclusion: </strong>Moderate and severe CIV compression were associated with increased IVT risk compared to no or mild compression. A decreasing degree of CIV compression was consistently associated with a decreasing risk of IVT when the minimum diameter was > 4.1 mm or the compression was < 61.0%.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"304-313"},"PeriodicalIF":2.8000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relationship Between Left Moderate or Severe Common Iliac Vein Compression and Occurrence of Involved Iliac Vein Thrombosis in Patients with Infrainguinal Deep Vein Thrombosis.\",\"authors\":\"Maofeng Gong, Rui Jiang, Xu He, Zhengcan Wu, Jianping Gu\",\"doi\":\"10.1007/s00270-025-03971-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To investigate the association between the degree of common iliac vein (CIV) compression and the incidence of iliac vein involvement thrombosis (IVT) in patients with infrainguinal deep vein thrombosis (DVT).</p><p><strong>Methods: </strong>This was a single center retrospective study. Between January 2015 and July 2023, infrainguinal DVT patients with or without IVT were included. Patient baseline demographics, clinical characteristics, and radiographic variables were collected and analyzed. Univariate analysis followed by multivariate analysis was used for IVT to determine odds ratio (OR) with a 95% confidence interval (CI). The association of the degree of CIV compression and IVT was evaluated by restricted cubic spines (RCS) on a continuous scale.</p><p><strong>Results: </strong>222 left-sided DVT patients [140 (63.1%) patients diagnosed with IVT, and 82 (36.9%) without] were included. Univariate analyses revealed a higher prevalence of female gender (55.7 vs. 41.5%, p = .040) and CIV compression among patients with left-sided IVT compared to those without IVT. After adjusting for female gender, a strong positive association between IVT and moderate (compression degree > 50% and ≤ 75%) (adjusted OR 3.75; 95% CI 1.571-8.974; p = .003) to severe (> 75%) (adjusted OR 4.05; 95% CI 1.615-10.134; p = .003) CIV compression degrees remained, indicating moderate or severe compression significantly increased IVT risk. RCS showed that a greater CIV minimum diameter or a smaller compression percentage was negatively associated with IVT incidence at a CIV minimum diameter was > 4.1 mm (p < .001) or compression percentage was < 61.0% (p < .001).</p><p><strong>Conclusion: </strong>Moderate and severe CIV compression were associated with increased IVT risk compared to no or mild compression. A decreasing degree of CIV compression was consistently associated with a decreasing risk of IVT when the minimum diameter was > 4.1 mm or the compression was < 61.0%.</p>\",\"PeriodicalId\":9591,\"journal\":{\"name\":\"CardioVascular and Interventional Radiology\",\"volume\":\" \",\"pages\":\"304-313\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"CardioVascular and Interventional Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00270-025-03971-6\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"CardioVascular and Interventional Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00270-025-03971-6","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/20 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
目的：探讨腹股沟下深静脉血栓形成（DVT）患者髂总静脉（CIV）受压程度与髂静脉受累血栓形成（IVT）发生率的关系。方法：本研究为单中心回顾性研究。2015年1月至2023年7月，纳入了腹股沟下DVT合并或不合并IVT的患者。收集并分析患者基线人口统计学、临床特征和影像学变量。IVT采用单因素分析和多因素分析确定优势比（OR）， 95%可信区间（CI）。通过限制性立方棘（RCS）在连续尺度上评估CIV压缩程度与IVT的关系。结果：纳入222例左侧DVT患者[诊断为IVT的患者140例（63.1%），未诊断为IVT的患者82例（36.9%）]。单因素分析显示，与未行左侧IVT的患者相比，行左侧IVT的患者女性患病率（55.7 vs. 41.5%, p = 0.040）和CIV压迫的发生率更高。在对女性性别进行调整后，IVT与中度（压迫程度> 50%和≤75%）有很强的正相关(调整OR为3.75；95% ci 1.571-8.974；p = 0.003)至重度（> 75%）(调整OR 4.05；95% ci 1.615-10.134；p = .003) civv压缩程度仍然存在，表明中度或重度压缩显著增加IVT风险。RCS显示较大的CIV最小直径或较小的压缩百分比与IVT发生率呈负相关，当CIV最小直径为>.1 mm时(p)。结论：与没有或轻度压缩相比，中度和重度CIV压缩与IVT风险增加相关。当最小直径为4.1 mm或最小直径为4.1 mm时，减小CIV压缩程度与减小IVT风险一致相关
Relationship Between Left Moderate or Severe Common Iliac Vein Compression and Occurrence of Involved Iliac Vein Thrombosis in Patients with Infrainguinal Deep Vein Thrombosis.
Purpose: To investigate the association between the degree of common iliac vein (CIV) compression and the incidence of iliac vein involvement thrombosis (IVT) in patients with infrainguinal deep vein thrombosis (DVT).
Methods: This was a single center retrospective study. Between January 2015 and July 2023, infrainguinal DVT patients with or without IVT were included. Patient baseline demographics, clinical characteristics, and radiographic variables were collected and analyzed. Univariate analysis followed by multivariate analysis was used for IVT to determine odds ratio (OR) with a 95% confidence interval (CI). The association of the degree of CIV compression and IVT was evaluated by restricted cubic spines (RCS) on a continuous scale.
Results: 222 left-sided DVT patients [140 (63.1%) patients diagnosed with IVT, and 82 (36.9%) without] were included. Univariate analyses revealed a higher prevalence of female gender (55.7 vs. 41.5%, p = .040) and CIV compression among patients with left-sided IVT compared to those without IVT. After adjusting for female gender, a strong positive association between IVT and moderate (compression degree > 50% and ≤ 75%) (adjusted OR 3.75; 95% CI 1.571-8.974; p = .003) to severe (> 75%) (adjusted OR 4.05; 95% CI 1.615-10.134; p = .003) CIV compression degrees remained, indicating moderate or severe compression significantly increased IVT risk. RCS showed that a greater CIV minimum diameter or a smaller compression percentage was negatively associated with IVT incidence at a CIV minimum diameter was > 4.1 mm (p < .001) or compression percentage was < 61.0% (p < .001).
Conclusion: Moderate and severe CIV compression were associated with increased IVT risk compared to no or mild compression. A decreasing degree of CIV compression was consistently associated with a decreasing risk of IVT when the minimum diameter was > 4.1 mm or the compression was < 61.0%.
期刊介绍：
CardioVascular and Interventional Radiology (CVIR) is the official journal of the Cardiovascular and Interventional Radiological Society of Europe, and is also the official organ of a number of additional distinguished national and international interventional radiological societies. CVIR publishes double blinded peer-reviewed original research work including clinical and laboratory investigations, technical notes, case reports, works in progress, and letters to the editor, as well as review articles, pictorial essays, editorials, and special invited submissions in the field of vascular and interventional radiology. Beside the communication of the latest research results in this field, it is also the aim of CVIR to support continuous medical education. Articles that are accepted for publication are done so with the understanding that they, or their substantive contents, have not been and will not be submitted to any other publication.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
