超过21年的A型颅内血肿:单一中心的经验

Jennifer Lynn Kim MD , Michael Baiocchi PhD , Matthew Leipzig BS , Matthew Duda MD , Edgar Aranda-Michel MD, PhD , Emily Tognozzi MS , Kelly Higa MD, PhD , Yuanjia Zhu MD, PhD , John Ward MacArthur MD , Y. Joseph Woo MD , Michael P. Fischbein MD, PhD
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引用次数: 0

摘要

目的评估2000年至2020年在同一医院治疗的A型分布型(TAIMH)和急性A型主动脉夹层(ATAAD)患者的短期和中期预后差异,以了解TAIMH的紧急手术治疗策略是否是可接受的治疗选择。方法:2000年1月至2020年12月,斯坦福医院共收治903例急性主动脉综合征患者。对该队列的基线特征、手术细节、短期术后结果、中期生存率和再手术率进行了检查。基数匹配用于控制基线特征和表现症状。采用精细平衡匹配对插管策略进行控制。结果经手术治疗的TAIMH患者187例,内科治疗27例。ATAAD组包括642名接受手术治疗的患者和47名非手术治疗的患者。与TAIMH手术患者相比,ATAAD手术患者多为男性,年轻化;然而,两组的其他基线病史相似。ATAAD患者表现出较高的灌注不良和主动脉反流率。在ATAAD组中,交叉钳夹和体外循环的时间更长,并且这些患者接受了更多的根置换。两组患者术后短期预后相似,未调整长期生存率和免于再次手术无显著差异。术前病史与表现症状的基数匹配,TAIMH患者中期生存率较好。在插管策略的良好平衡匹配下,两组中期生存率和卒中发生率无显著差异。结论:急性TAIMH的外科治疗策略可获得良好的术后效果,并支持在主动脉中心采用积极的紧急手术策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Type A intramural hematoma over 21 years: A single center's experience

Objective

To evaluate the differences in short- and mid-term outcomes for intramural hematoma in the type A distribution (TAIMH) and acute type A aortic dissection (ATAAD) patients treated at a single institution between 2000 and 2020 to provide insight into whether an emergent surgical treatment strategy for TAIMH is an acceptable treatment option.

Methods

Between January 2000 and December 2020, a total of 903 patients were treated for acute aortic syndrome at Stanford Hospital. Baseline characteristics, operative details, short-term postoperative outcomes, mid-term survival, and reoperation rates were examined for this cohort. Cardinality matching was used to control for baseline characteristics and presentation symptoms. Fine balance matching was used to control for cannulation strategy.

Results

A total of 187 TAIMH patients were treated surgically and 27 were managed medically. The ATAAD arm included 642 patients who underwent surgery and 47 who were managed nonoperatively. ATAAD operative patients were more commonly male and younger compared to the TAIMH operative patients; however, other baseline medical history was similar in the 2 arms. ATAAD patients presented with higher rates of malperfusion and aortic regurgitation. Cross-clamp and cardiopulmonary bypass times were longer in the ATAAD arm, and these patients underwent more root replacements. Short-term postoperative outcomes were similar in the 2 arms, and there was no significant difference in unadjusted long-term survival and freedom from reoperation. With cardinality matching for preoperative history and presentation symptoms, mid-term survival was better for TAIMH patients. With fine balance matching for cannulation strategy, there was no significant difference between the groups in mid-term survival or stroke.

Conclusions

In conclusion, a surgical management strategy for acute TAIMH results in excellent postoperative outcomes and supports an aggressive emergent operative strategy in aortic centers of excellence.
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