翻盖胸骨切开术一期修复部分主动脉弓病变

Neel K. Prabhu MD, Andrew M. Vekstein MD, Christopher W. Jensen MD, MS, Adam R. Williams MD, Jeffrey G. Gaca MD, G. Chad Hughes MD
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引用次数: 0

摘要

目的虽然胸骨正中切开术广泛应用于主动脉弓修复,但该入路的远端弓置换术范围有限。双侧胸廓切开术(翻盖术)是一种替代的、未被重视的策略,允许单阶段修复主动脉弓和胸降主动脉。我们报告了我们使用这种方法的机构经验。方法从一个前瞻性维护的机构主动脉手术数据库中筛选2005年至2022年在主动脉弓手术中接受翻盖胸骨切开术的患者。主要结局是30天/住院死亡率和主要发病率,包括中风、截瘫和需要血液透析的肾衰竭。次要结局包括晚期总生存、主动脉特异性生存和主动脉再干预的自由。结果18例患者行翻盖胸骨切开术(男性67%),中位年龄52岁;50% (n = 9)有遗传性胸主动脉疾病。翻盖修复指征包括局灶性弓夹层(44%;N = 8),广泛弓动脉瘤或假性动脉瘤(33%;N = 6),复杂性小儿缩窄(17%;N = 3),成人缩窄伴升动脉瘤(6%;n = 1)。1例患者发生手术死亡(6%)。没有患者发生中风、截瘫或肾衰竭。总体精算生存率为1年94%,5年72%,而主动脉特异性生存率为1年和5年94%。在中位随访60个月(范围18-85个月)期间,未对邻近主动脉进行再干预。结论对于有遗传性胸主动脉疾病或解剖结构不适合血管内治疗的患者,翻盖胸骨切开术是一种安全的治疗单期复杂开弓的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clamshell thoracosternotomy for single-stage repair of select aortic arch pathologies

Objective

Although median sternotomy is widely used for aortic arch repair, the distal extent of arch replacement is limited with this approach. Bilateral thoracosternotomy (clamshell) represents an alternate and underappreciated strategy that allows for single-stage repair of the aortic arch and descending thoracic aorta. We report our institutional experience with this approach.

Methods

Patients who underwent clamshell thoracosternotomy for aortic arch surgery from 2005 to 2022 were identified from a prospectively maintained institutional aortic surgery database. The primary outcomes were 30-day/in-hospital mortality and major morbidity, including stroke, paraplegia, and renal failure requiring hemodialysis. Secondary outcomes included late overall survival, aorta-specific survival, and freedom from aortic reintervention.

Results

Clamshell thoracosternotomy was performed in 18 patients (67% men) with median age 52 years; 50% (n = 9) had heritable thoracic aortic disease. Clamshell repair indications included focal arch dissection (44%; n = 8), extensive arch aneurysm or pseudoaneurysm (33%; n = 6), complex pediatric coarctation (17%; n = 3), and adult coarctation with ascending aneurysm (6%; n = 1). Operative mortality occurred in 1 patient (6%). No patients developed stroke, paraplegia, or renal failure. Overall actuarial survival was 94% at 1 year and 72% at 5 years, whereas aorta-specific survival was 94% at 1 and 5 years. There were no reinterventions on the contiguous aorta at a median follow-up of 60 months (range, 18-85 months).

Conclusions

Clamshell thoracosternotomy is a safe approach for single-stage complex open arch with or without descending repair, especially for those with heritable thoracic aortic disease or anatomy not amenable to endovascular therapies.
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