右截尾数据的变系数比例平均剩余寿命模型。

IF 1.8 4区 医学 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Bing Wang, Xinyuan Song, Qian Zhao
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引用次数: 0

摘要

平均剩余寿命提供了存活到特定时间点的受试者的剩余预期寿命。本文考虑了一个变系数的比例平均剩余寿命模型,该模型允许人们探索一些协变量与暴露变量之间的非线性相互作用。在半参数条件下,我们构造了局部估计方程来得到变系数,并建立了所提估计量的渐近正态性。此外,研究了基线平均剩余寿命函数的局部估计量的弱收敛性。我们进行模拟研究,以经验检验所提出方法的有限样本性能,并将该方法应用于2型糖尿病并发症的现实数据集。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Proportional Mean Residual Life Model With Varying Coefficients for Right Censored Data.

The mean residual life provides the remaining life expectancy of a subject who has survived to a specific time point. This paper considers a proportional mean residual life model with varying coefficients, which allows one to explore the nonlinear interactions between some covariates and an exposure variable. In a semiparametric setting, we construct local estimating equations to obtain the varying coefficients and establish the asymptotic normality of the proposed estimators. Moreover, the weak convergence property for the local estimator of the baseline mean residual life function is developed. We conduct simulation studies to empirically examine the finite-sample performance of the proposed methods and apply the methodology to a real-life dataset on type 2 diabetic complications.

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来源期刊
Statistics in Medicine
Statistics in Medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.40
自引率
10.00%
发文量
334
审稿时长
2-4 weeks
期刊介绍: The journal aims to influence practice in medicine and its associated sciences through the publication of papers on statistical and other quantitative methods. Papers will explain new methods and demonstrate their application, preferably through a substantive, real, motivating example or a comprehensive evaluation based on an illustrative example. Alternatively, papers will report on case-studies where creative use or technical generalizations of established methodology is directed towards a substantive application. Reviews of, and tutorials on, general topics relevant to the application of statistics to medicine will also be published. The main criteria for publication are appropriateness of the statistical methods to a particular medical problem and clarity of exposition. Papers with primarily mathematical content will be excluded. The journal aims to enhance communication between statisticians, clinicians and medical researchers.
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