阿米硫pride治疗儿童和青少年精神疾病的安全性和临床效果：一个病例系列。

IF 1.5 4区医学 Q2 PEDIATRICS

Journal of child and adolescent psychopharmacology Pub Date : 2025-06-01 Epub Date: 2025-02-17 DOI:10.1089/cap.2024.0139

Osman Özdemir

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引用次数: 0

摘要

目的：本研究的目的是探讨氨硫pride在患有精神疾病的儿童和青少年中的安全性和临床效果。方法：该病例系列包括6例患者，年龄11至19岁，诊断为情感性障碍、自闭症、焦虑、精神病和强迫症，并以每天100至400mg剂量的阿米硫pride进行治疗。结果：氨硫傲可减轻精神病和行为症状。观察到的副作用包括食欲增加、体重增加、镇静和轻微的锥体外系症状。结论：氨硫pride在有精神障碍和严重症状的儿童和青少年中可能有研究和未来使用的希望。

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The Safety and Clinical Effects of Amisulpride in Children and Adolescents with Psychiatric Disorders: A Case Series.

Objectives: The objective of this study was to explore the safety and clinical effects of amisulpride in children and adolescents with psychiatric disorders. Methods: This case series included six patients, aged 11 to 19 years, diagnosed with affective disorder, autism, anxiety, psychosis, and obsessive-compulsive disorder, and treated with amisulpride at doses ranging from 100 to 400 mg per day. Results: Amisulpride appeared to reduce psychotic and behavioral symptoms. Observed side effects included increased appetite, weight gain, sedation, and mild extrapyramidal symptoms. Conclusion: Amisulpride may have promise for study and future use in children and adolescents with psychiatric disorders and severe symptoms.

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来源期刊

Journal of child and adolescent psychopharmacology 医学-精神病学

CiteScore

3.60

自引率

5.30%

发文量

审稿时长

>12 weeks

期刊介绍： Journal of Child and Adolescent Psychopharmacology (JCAP) is the premier peer-reviewed journal covering the clinical aspects of treating this patient population with psychotropic medications including side effects and interactions, standard doses, and research on new and existing medications. The Journal includes information on related areas of medical sciences such as advances in developmental pharmacokinetics, developmental neuroscience, metabolism, nutrition, molecular genetics, and more. Journal of Child and Adolescent Psychopharmacology coverage includes: New drugs and treatment strategies including the use of psycho-stimulants, selective serotonin reuptake inhibitors, mood stabilizers, and atypical antipsychotics New developments in the diagnosis and treatment of ADHD, anxiety disorders, schizophrenia, autism spectrum disorders, bipolar disorder, eating disorders, along with other disorders Reports of common and rare Treatment Emergent Adverse Events (TEAEs) including: hyperprolactinemia, galactorrhea, weight gain/loss, metabolic syndrome, dyslipidemia, switching phenomena, sudden death, and the potential increase of suicide. Outcomes research.