Alejandro Salvado, Lilian Capone, Paula Zamorano, Mayra Samudio, María Teresa Garcia-de-Dávila, Glenda Ernst
{"title":"确定地下工人石棉暴露的综合多学科方法。","authors":"Alejandro Salvado, Lilian Capone, Paula Zamorano, Mayra Samudio, María Teresa Garcia-de-Dávila, Glenda Ernst","doi":"10.47626/1679-4435-2024-1271","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Inhalation of asbestos fibers can lead to a range of diseases, including asbestosis, pleural plaques, lung cancer, and malignant mesothelioma. Despite regulatory efforts, asbestos-related diseases remain a significant public health issue.</p><p><strong>Objectives: </strong>This study aimed to assess the characteristics and prevalence of asbestos-related diseases among exposed workers.</p><p><strong>Methods: </strong>We conducted a descriptive cohort study with underground workers in Buenos Aires, Argentina, from March 2018 to March 2023. A comprehensive screening and surveillance program, including medical examinations, was implemented to identify exposure-related signs and symptoms. Histological sections from paraffin-embedded tissue blocks were analyzed using light and polarization microscopy for lung cancer cases.</p><p><strong>Results: </strong>A total of 2,690 participants were included, of whom 2.8% (n = 77) had asbestos-related diseases and 0.22% (n = 6) had lung cancer. Occupational exposure exceeding 20 years was significantly associated with an elevated risk of asbestos-related diseases (odd ratio: 3.02; 95%CI 1.7-5.3).</p><p><strong>Conclusions: </strong>The prevalence of occupational diseases among underground workers was consistent with findings from other surveillance programs for asbestos-exposed workers. Occupational exposure exceeding 20 years emerged as a significant risk factor, markedly increasing the likelihood of asbestos-related diseases.</p>","PeriodicalId":38694,"journal":{"name":"Revista Brasileira de Medicina do Trabalho","volume":"22 4","pages":"e20241271"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822978/pdf/","citationCount":"0","resultStr":"{\"title\":\"A comprehensive multidisciplinary approach for identifying asbestos exposure among underground workers.\",\"authors\":\"Alejandro Salvado, Lilian Capone, Paula Zamorano, Mayra Samudio, María Teresa Garcia-de-Dávila, Glenda Ernst\",\"doi\":\"10.47626/1679-4435-2024-1271\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Inhalation of asbestos fibers can lead to a range of diseases, including asbestosis, pleural plaques, lung cancer, and malignant mesothelioma. Despite regulatory efforts, asbestos-related diseases remain a significant public health issue.</p><p><strong>Objectives: </strong>This study aimed to assess the characteristics and prevalence of asbestos-related diseases among exposed workers.</p><p><strong>Methods: </strong>We conducted a descriptive cohort study with underground workers in Buenos Aires, Argentina, from March 2018 to March 2023. A comprehensive screening and surveillance program, including medical examinations, was implemented to identify exposure-related signs and symptoms. Histological sections from paraffin-embedded tissue blocks were analyzed using light and polarization microscopy for lung cancer cases.</p><p><strong>Results: </strong>A total of 2,690 participants were included, of whom 2.8% (n = 77) had asbestos-related diseases and 0.22% (n = 6) had lung cancer. Occupational exposure exceeding 20 years was significantly associated with an elevated risk of asbestos-related diseases (odd ratio: 3.02; 95%CI 1.7-5.3).</p><p><strong>Conclusions: </strong>The prevalence of occupational diseases among underground workers was consistent with findings from other surveillance programs for asbestos-exposed workers. Occupational exposure exceeding 20 years emerged as a significant risk factor, markedly increasing the likelihood of asbestos-related diseases.</p>\",\"PeriodicalId\":38694,\"journal\":{\"name\":\"Revista Brasileira de Medicina do Trabalho\",\"volume\":\"22 4\",\"pages\":\"e20241271\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822978/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Brasileira de Medicina do Trabalho\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47626/1679-4435-2024-1271\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Brasileira de Medicina do Trabalho","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47626/1679-4435-2024-1271","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A comprehensive multidisciplinary approach for identifying asbestos exposure among underground workers.
Introduction: Inhalation of asbestos fibers can lead to a range of diseases, including asbestosis, pleural plaques, lung cancer, and malignant mesothelioma. Despite regulatory efforts, asbestos-related diseases remain a significant public health issue.
Objectives: This study aimed to assess the characteristics and prevalence of asbestos-related diseases among exposed workers.
Methods: We conducted a descriptive cohort study with underground workers in Buenos Aires, Argentina, from March 2018 to March 2023. A comprehensive screening and surveillance program, including medical examinations, was implemented to identify exposure-related signs and symptoms. Histological sections from paraffin-embedded tissue blocks were analyzed using light and polarization microscopy for lung cancer cases.
Results: A total of 2,690 participants were included, of whom 2.8% (n = 77) had asbestos-related diseases and 0.22% (n = 6) had lung cancer. Occupational exposure exceeding 20 years was significantly associated with an elevated risk of asbestos-related diseases (odd ratio: 3.02; 95%CI 1.7-5.3).
Conclusions: The prevalence of occupational diseases among underground workers was consistent with findings from other surveillance programs for asbestos-exposed workers. Occupational exposure exceeding 20 years emerged as a significant risk factor, markedly increasing the likelihood of asbestos-related diseases.