中等收入国家急性A型主动脉夹层全弓置换术是安全的。

IF 1.2
Juan David Niño-Calvera, Julian Senosiain, Nicolas Nuñez-Ordonez, Ivonne Pineda, Lina Ramírez, Carlos Villa, Carlos Obando, Tomas Chalela, Nestor Sandoval, Juan P Umaña, Jaime Camacho
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引用次数: 0

摘要

目的:本研究的目的是确定急性A型主动脉夹层患者的临床结果,比较近端主动脉修复与全弓置换术。方法:回顾性队列研究。我们纳入了2002年1月至2022年11月期间所有急性A型主动脉夹层手术。根据主动脉置换术的程度(血弓修复vs全弓置换术)来划分组。我们收集了术前、术中和术后变量的数据。我们的主要终点是卒中率、脊髓损伤和住院死亡率。我们根据变量的性质和分布进行组间比较的统计分析。双变量分析采用Mann-Whitney U检验,分类变量采用卡方检验或Fisher精确检验。在0.05的α水平上建立显著性。结果:我们确定了107例急性A型主动脉夹层手术(69例主动脉弓修复,38例全动脉弓置换)。两组在手术部位感染或急性肾损伤等术后结局方面无差异。出血再手术在充血组更常见(30%比11%)。我们没有发现卒中发生率、脊髓损伤或住院死亡率有统计学意义的差异。结论:急性A型主动脉夹层的治疗仍是一个挑战。与血弓修复术相比,全弓置换术不会增加术后早期主要并发症的风险。延长修复似乎提供了诸如降低再手术风险等好处。全弓置换术应在特定的患者中进行,因为它可以改善长期预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Total Arch Replacement is Safe as Hemiarch Repair in Acute Type A Aortic Dissection in a Middle-Income Country Setting.

Total Arch Replacement is Safe as Hemiarch Repair in Acute Type A Aortic Dissection in a Middle-Income Country Setting.

Total Arch Replacement is Safe as Hemiarch Repair in Acute Type A Aortic Dissection in a Middle-Income Country Setting.

Objectiver: The aim of this study was to determine the clinical outcomes of patients with acute type A aortic dissection comparing proximal aortic repair vs. total arch replacement.

Methods: This was a retrospective cohort study. We included all acute type A aortic dissection procedures from January 2002 to November 2022. Groups were defined according to the extent of aortic replacement (hemiarch repair vs. total arch replacement). We collected data from pre, intra, and postoperative variables. Our main endpoints were stroke rate, spinal cord injury, and in-hospital mortality. We performed a statistical analysis for between-group comparisons according to the nature and distribution of variables. Bivariate analyses were done using the Mann-Whitney U test and for categorical variables, the Chi-square test or Fisher's exact test. Significance was established at alpha level of 0.05.

Results: We identified 107 acute type A aortic dissection procedures (69 hemiarch repairs vs. 38 total arch replacements). There were no differences in postoperative outcomes such as surgical site infection or acute kidney injury. Bleeding reoperation was more frequent in the hemiarch group (30% vs. 11 %). We did not find statistically significant differences in stroke rate, spinal cord injury, or in-hospital mortality.

Conclusion: Acute type A aortic dissection treatment is still a challenge. Total arch replacement does not increase the risk of major early postoperative complications in comparison to hemiarch repair. The extended repair seems to provide benefits such as a lower risk of reoperation. Total arch replacement should be performed in selected patients, as it may improve long-term outcomes.

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