基于超声的放射基因组学:现状、应用和未来方向。

IF 2.4 3区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Ultrasonography Pub Date : 2025-03-01 Epub Date: 2024-12-12 DOI:10.14366/usg.24152
Si-Rui Wang, Yu-Ting Shen, Bin Huang, Hui-Xiong Xu
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引用次数: 0

摘要

放射基因组学是放射组学的延伸,探索成像特征与潜在基因表达模式之间的关系。该领域有助于提供可靠的成像替代品,因此可能代表基因检测的替代方法。利用超声(US)成像的放射基因组学迅速发展,旨在阐明超声图像特征与基因组数据之间的联系。本文概述了放射基因组学的工作流程,并对美国放射基因组学的应用进行了综述。这些包括基因变异、分子亚型和其他生物学特征的预测,以及美国表型和癌症基因谱之间关系的探索。尽管该领域面临各种挑战,但美国的放射基因组学为未来的研究提供了有希望的前景和途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ultrasound-based radiogenomics: status, applications, and future direction.

Radiogenomics, an extension of radiomics, explores the relationship between imaging features and underlying gene expression patterns. This field is instrumental in providing reliable imaging surrogates, thus potentially representing an alternative to genetic testing. The rapidly growing area of radiogenomics that utilizes ultrasound (US) imaging seeks to elucidate the connections between US image characteristics and genomic data. In this review, the authors outline the radiogenomics workflow and summarize the applications of US-based radiogenomics. These include the prediction of gene variations, molecular subtypes, and other biological characteristics, as well as the exploration of the relationships between US phenotypes and cancer gene profiles. Although the field faces various challenges, US-based radiogenomics offers promising prospects and avenues for future research.

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来源期刊
Ultrasonography
Ultrasonography Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
5.10
自引率
6.50%
发文量
78
审稿时长
15 weeks
期刊介绍: Ultrasonography, the official English-language journal of the Korean Society of Ultrasound in Medicine (KSUM), is an international peer-reviewed academic journal dedicated to practice, research, technology, and education dealing with medical ultrasound. It is renamed from the Journal of Korean Society of Ultrasound in Medicine in January 2014, and published four times per year: January 1, April 1, July 1, and October 1. Original articles, technical notes, topical reviews, perspectives, pictorial essays, and timely editorial materials are published in Ultrasonography covering state-of-the-art content. Ultrasonography aims to provide updated information on new diagnostic concepts and technical developments, including experimental animal studies using new equipment in addition to well-designed reviews of contemporary issues in patient care. Along with running KSUM Open, the annual international congress of KSUM, Ultrasonography also serves as a medium for cooperation among physicians and specialists from around the world who are focusing on various ultrasound technology and disease problems and relevant basic science.
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