Yağmur Demirel, Sevgi Kesici, Celal Kaya, Sibel Oba, Hacer Şebnem Türk
{"title":"1型戊二酸尿孕妇剖宫产术的麻醉处理。","authors":"Yağmur Demirel, Sevgi Kesici, Celal Kaya, Sibel Oba, Hacer Şebnem Türk","doi":"10.4274/TJAR.2025.241705","DOIUrl":null,"url":null,"abstract":"<p><p>Glutaric aciduria type 1 (GA-1) presents unique challenges for anaesthetists. This case report discusses anaesthesia management in a pregnant woman with GA-1 undergoing cesarean delivery. Based on a cautious consideration of potential complications, combined spinal-epidural anaesthesia was preferred in this case. Maintenance of normoglycemia, normothermia, low-protein diet, carnitine supplementation, and proper hydration were prioritized. A healthy baby was delivered without complications. This case underscores the importance of comprehensive preoperative assessment and individualized anaesthesia strategies for achieving optimal outcomes in pregnant patients with GA-1. The cautious management of anaesthesia-related risks is important to ensure patient safety and decrease stress responses. Neuraxial anaesthesia and analgesia may be advantageous in specific cases.</p>","PeriodicalId":23353,"journal":{"name":"Turkish journal of anaesthesiology and reanimation","volume":"53 1","pages":"28-30"},"PeriodicalIF":0.9000,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827511/pdf/","citationCount":"0","resultStr":"{\"title\":\"Anaesthesia Management of a Pregnant Woman with Glutaric Aciduria Type 1 Undergoing Cesarean Section.\",\"authors\":\"Yağmur Demirel, Sevgi Kesici, Celal Kaya, Sibel Oba, Hacer Şebnem Türk\",\"doi\":\"10.4274/TJAR.2025.241705\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Glutaric aciduria type 1 (GA-1) presents unique challenges for anaesthetists. This case report discusses anaesthesia management in a pregnant woman with GA-1 undergoing cesarean delivery. Based on a cautious consideration of potential complications, combined spinal-epidural anaesthesia was preferred in this case. Maintenance of normoglycemia, normothermia, low-protein diet, carnitine supplementation, and proper hydration were prioritized. A healthy baby was delivered without complications. This case underscores the importance of comprehensive preoperative assessment and individualized anaesthesia strategies for achieving optimal outcomes in pregnant patients with GA-1. The cautious management of anaesthesia-related risks is important to ensure patient safety and decrease stress responses. Neuraxial anaesthesia and analgesia may be advantageous in specific cases.</p>\",\"PeriodicalId\":23353,\"journal\":{\"name\":\"Turkish journal of anaesthesiology and reanimation\",\"volume\":\"53 1\",\"pages\":\"28-30\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-02-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827511/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Turkish journal of anaesthesiology and reanimation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4274/TJAR.2025.241705\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Turkish journal of anaesthesiology and reanimation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/TJAR.2025.241705","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Anaesthesia Management of a Pregnant Woman with Glutaric Aciduria Type 1 Undergoing Cesarean Section.
Glutaric aciduria type 1 (GA-1) presents unique challenges for anaesthetists. This case report discusses anaesthesia management in a pregnant woman with GA-1 undergoing cesarean delivery. Based on a cautious consideration of potential complications, combined spinal-epidural anaesthesia was preferred in this case. Maintenance of normoglycemia, normothermia, low-protein diet, carnitine supplementation, and proper hydration were prioritized. A healthy baby was delivered without complications. This case underscores the importance of comprehensive preoperative assessment and individualized anaesthesia strategies for achieving optimal outcomes in pregnant patients with GA-1. The cautious management of anaesthesia-related risks is important to ensure patient safety and decrease stress responses. Neuraxial anaesthesia and analgesia may be advantageous in specific cases.