重症监护病房急性肾损伤患者的临床特征、预后和转归。

Q3 Medicine
Divendu Bhushan, Vijay Kumar, Ria Roy, Chandrima Pattadar, Aniketh Hegde, Sudheer Y Verma
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引用次数: 0

摘要

背景:急性肾损伤(AKI)是重症监护病房(ICU)预后较差的疾病之一。它增加了死亡率。其病理生理涉及多个方面,如肾、肾和肾后成分。很多时候,它是一种或多种病因的组合。它的管理是一个挑战,因为没有任何药物被批准用于预防或治疗它。最重要的是全面的治疗和及时的肾替代疗法(RRT)。为了了解AKI患者的预后和转归,我们进行了这项观察性分析研究。材料与方法:为观察性研究。为了分析循环利尿剂的效果,我们将患者分为两组:一组使用速尿,另一组不使用速尿。结果:AKI患者以男性为主。高血压和糖尿病是最常见的合并症。约44.1%的患者使用利尿剂。患者对RRT的需求和血管加压药物的需求没有显著差异;然而,接受利尿剂治疗的患者预后更差。结论:利尿剂的使用并不能改善急性肾损伤的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Profile, Prognosis, and Outcome of Acute Kidney Injury Patients Admitted in Medical Intensive Care Unit.

Background: Acute kidney injury (AKI) is one of the poor prognosticating conditions in the intensive care unit (ICU). It increases mortality. Its pathophysiology involves various aspects, such as prerenal, renal, and postrenal components. Many times, it is a combination of one or more etiologies. Its management is a challenge, as no agent is approved for its prevention or treatment. It is the comprehensive treatment and timely institution of renal replacement therapy (RRT) that matter most. To understand the prognosis and outcome of patients with AKI, we conducted this observational analytical study.

Materials and methods: It was a observational study. To analyze the effect of loop diuretics, we grouped the patients into two: one group received furosemide, and the other did not.

Results: There was a male preponderance among AKI patients. Hypertension and diabetes were the most common comorbidities. About 44.1% of patients received diuretics. There was no significant difference among patients in the requirement for RRT or the need for vasopressors; however, the outcome of patients who received diuretics was worse.

Conclusion: The use of diuretics did not improve the outcome of acute kidney injury.

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