{"title":"重症监护病房急性肾损伤患者的临床特征、预后和转归。","authors":"Divendu Bhushan, Vijay Kumar, Ria Roy, Chandrima Pattadar, Aniketh Hegde, Sudheer Y Verma","doi":"10.59556/japi.73.0827","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Acute kidney injury (AKI) is one of the poor prognosticating conditions in the intensive care unit (ICU). It increases mortality. Its pathophysiology involves various aspects, such as prerenal, renal, and postrenal components. Many times, it is a combination of one or more etiologies. Its management is a challenge, as no agent is approved for its prevention or treatment. It is the comprehensive treatment and timely institution of renal replacement therapy (RRT) that matter most. To understand the prognosis and outcome of patients with AKI, we conducted this observational analytical study.</p><p><strong>Materials and methods: </strong>It was a observational study. To analyze the effect of loop diuretics, we grouped the patients into two: one group received furosemide, and the other did not.</p><p><strong>Results: </strong>There was a male preponderance among AKI patients. Hypertension and diabetes were the most common comorbidities. About 44.1% of patients received diuretics. There was no significant difference among patients in the requirement for RRT or the need for vasopressors; however, the outcome of patients who received diuretics was worse.</p><p><strong>Conclusion: </strong>The use of diuretics did not improve the outcome of acute kidney injury.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 2","pages":"23-25"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical Profile, Prognosis, and Outcome of Acute Kidney Injury Patients Admitted in Medical Intensive Care Unit.\",\"authors\":\"Divendu Bhushan, Vijay Kumar, Ria Roy, Chandrima Pattadar, Aniketh Hegde, Sudheer Y Verma\",\"doi\":\"10.59556/japi.73.0827\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Acute kidney injury (AKI) is one of the poor prognosticating conditions in the intensive care unit (ICU). It increases mortality. Its pathophysiology involves various aspects, such as prerenal, renal, and postrenal components. Many times, it is a combination of one or more etiologies. Its management is a challenge, as no agent is approved for its prevention or treatment. It is the comprehensive treatment and timely institution of renal replacement therapy (RRT) that matter most. To understand the prognosis and outcome of patients with AKI, we conducted this observational analytical study.</p><p><strong>Materials and methods: </strong>It was a observational study. To analyze the effect of loop diuretics, we grouped the patients into two: one group received furosemide, and the other did not.</p><p><strong>Results: </strong>There was a male preponderance among AKI patients. Hypertension and diabetes were the most common comorbidities. About 44.1% of patients received diuretics. There was no significant difference among patients in the requirement for RRT or the need for vasopressors; however, the outcome of patients who received diuretics was worse.</p><p><strong>Conclusion: </strong>The use of diuretics did not improve the outcome of acute kidney injury.</p>\",\"PeriodicalId\":22693,\"journal\":{\"name\":\"The Journal of the Association of Physicians of India\",\"volume\":\"73 2\",\"pages\":\"23-25\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of the Association of Physicians of India\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.59556/japi.73.0827\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of the Association of Physicians of India","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.59556/japi.73.0827","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Clinical Profile, Prognosis, and Outcome of Acute Kidney Injury Patients Admitted in Medical Intensive Care Unit.
Background: Acute kidney injury (AKI) is one of the poor prognosticating conditions in the intensive care unit (ICU). It increases mortality. Its pathophysiology involves various aspects, such as prerenal, renal, and postrenal components. Many times, it is a combination of one or more etiologies. Its management is a challenge, as no agent is approved for its prevention or treatment. It is the comprehensive treatment and timely institution of renal replacement therapy (RRT) that matter most. To understand the prognosis and outcome of patients with AKI, we conducted this observational analytical study.
Materials and methods: It was a observational study. To analyze the effect of loop diuretics, we grouped the patients into two: one group received furosemide, and the other did not.
Results: There was a male preponderance among AKI patients. Hypertension and diabetes were the most common comorbidities. About 44.1% of patients received diuretics. There was no significant difference among patients in the requirement for RRT or the need for vasopressors; however, the outcome of patients who received diuretics was worse.
Conclusion: The use of diuretics did not improve the outcome of acute kidney injury.