青少年股骨远端皮质不规则的患病率及危险因素

IF 1.5 Q3 ORTHOPEDICS

Journal of orthopaedics Pub Date : 2025-02-06 DOI:10.1016/j.jor.2025.02.007

Andrew Gaukroger , Abrar Gani , Philip Martin Sedgwick , Diego Agustín Abelleyra Lastoria , Antoine Corentin Georges Kerouedan , Vivian Ejindu , Anshul Rastogi , Caroline Blanca Hing

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引用次数: 0

摘要

股骨远端皮质不规则性（DFCI）的发病机制和患病率尚不确定。我们的目的是评估在接受MRI的青少年队列中DFCI的患病率，并识别和评估相关的危险因素。方法对接受MRI扫描的青少年（10 - 20岁）进行历史队列研究。使用一家大型三级医院的图片存档和通信系统数据库收集了5年的数据。收集的数据包括性别、年龄、损伤机制和原始MRI报告中出现的其他病理。采用二元logistic回归分析DFCI的潜在危险因素。结果897次扫描，平均年龄15.3岁（SD 2.59）；499例（55.6%）为男性。在接受MRI扫描的青少年中，DFCI患病率为9.1% （95% CI: 7.3% - 11.2%）。经历过DFCI的患者比没有经历过DFCI的患者年轻（平均年龄14.5岁vs 15.3岁，P = 0.002）。损伤机制组间差异有统计学意义（P = 0.015）；DFCI患者更有可能发生髌骨不稳定/脱位（22.8%对16.1%），而发生关键膝关节损伤的可能性更小（12.7%对29.0%）。与10-13岁的患者相比，年龄较大的儿童发生DFCI的几率降低：13-16岁的调整优势比（aOR）为0.79 (95% CI: 0.45至1.39)；16 ~ 20岁(aOR = 0.36；95% CI: 0.18 ~ 0.71)。男性患DFCI的几率较低(aOR = 0.38；95% CI: 0.22 ~ 0.66)。结论女性和低龄化是DFCI发生的危险因素。损伤机制与发生DFCI之间无统计学意义的关联。需要进一步的研究来确定其在无症状者中的患病率，以及为什么年轻的青春期女性更有可能经历DFCI。

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The prevalence of, and risk factors for distal femoral cortical irregularity in the adolescent population

Introduction

There is uncertainty around the pathogenesis and prevalence of distal femoral cortical irregularities (DFCI). We aimed to assess the prevalence of DFCI in a cohort of adolescents that underwent MRI and identify and assess associated risk factors.

Methods

A historical cohort study of adolescents (age 10 - <20 years) undergoing MRI scans was conducted. Data was collected for a period of five years using the Picture Archive and Communication System database at a large tertiary hospital. Data collected included sex, age, mechanism of injury and other pathology present in the original MRI report. Binary logistic regression was used to investigate potential risk factors for DFCI.

Results

897 scans (mean age, 15.3 (SD 2.59) years; 499 (55.6 %) male) were analysed. Prevalence of DFCI among adolescents who had a MRI scan was 9.1 % (95 % CI: 7.3 %–11.2 %). Patients that had experienced DFCI were younger than those that had not (mean age 14.5 vs 15.3 years, P = 0.002). The mechanism of injury differed between patient groups (P = 0.015); Patients with DFCI were more likely to have had a patella instability/dislocation (22.8 % vs 16.1 %), and less likely to have had a pivotal knee injury (12.7 % vs 29.0 %). When compared to patients aged 10–13 years, older children had reduced odds of a DFCI: 13–16 years had an adjusted odds ratio (aOR) of 0.79 (95 % CI: 0.45 to 1.39); 16–20 years (aOR = 0.36; 95 % CI: 0.18 to 0.71). Males had reduced odds of a DFCI (aOR = 0.38; 95 % CI: 0.22 to 0.66).

Conclusions

Female sex and younger age were risk factors for development of DFCI. There was no statistically significant association between mechanism of injury and developing a DFCI. Further research is required to establish its prevalence in those who are asymptomatic and why younger adolescent females are more likely to experience DFCI.

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来源期刊

Journal of orthopaedics ORTHOPEDICS-

CiteScore

3.50

自引率

6.70%

发文量

202

审稿时长

56 days

期刊介绍： Journal of Orthopaedics aims to be a leading journal in orthopaedics and contribute towards the improvement of quality of orthopedic health care. The journal publishes original research work and review articles related to different aspects of orthopaedics including Arthroplasty, Arthroscopy, Sports Medicine, Trauma, Spine and Spinal deformities, Pediatric orthopaedics, limb reconstruction procedures, hand surgery, and orthopaedic oncology. It also publishes articles on continuing education, health-related information, case reports and letters to the editor. It is requested to note that the journal has an international readership and all submissions should be aimed at specifying something about the setting in which the work was conducted. Authors must also provide any specific reasons for the research and also provide an elaborate description of the results.