{"title":"肌肉结构对女性膝关节骨性关节炎患者功能表现的决定作用","authors":"Nazli Cigercioglu, Zilan Bazancir-Apaydin, Ezgi Unuvar-Yuksel, Hakan Apaydin, Gul Baltaci, Hande Guney-Deniz","doi":"10.1002/pri.70030","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and purpose: </strong>Knee osteoarthritis (KOA) is associated with early muscular alterations and muscle weakness, which contribute to disease progression. However, limited knowledge exists regarding the potential exacerbation of lower extremity muscle architecture and its impact on functional performance. This study aimed to investigate the relationship between knee extensor and ankle plantar flexor muscle architecture, femoral cartilage thickness, age, body mass index (BMI), pain severity, and functional performance in middle-aged women with KOA.</p><p><strong>Methods: </strong>A total of 87 patients diagnosed with KOA (mean age = 51.48 ± 4.89 years, mean BMI = 27.96 ± 4.66 kg/m<sup>2</sup>) were included in the study. Ultrasonography was used to assess muscle thickness, adipose tissue thickness, pennation angle, and the muscle/adipose tissue thickness ratio (MATR) of the Rectus Femoris (RF), Vastus Medialis (VM), Vastus Lateralis (VL), and Medial Gastrocnemius (MG) muscles. Physical performance was evaluated through the stair-climbing test and the 10-time sit to stand test. Pearson's correlation test and multiple linear regression analysis were used.</p><p><strong>Results: </strong>The pennation angle of the VL and pain level predicted sit to stand test results; the pennation angle of RF, age, BMI and pain level predicted stair-climbing test results (p < 0.001). Femoral cartilage thickness at the medial condyle, intercondylar area, and lateral condyle correlated with performance in both tests (p < 0.001). Additionally, age, BMI, pain intensity, muscle thickness, pennation angle and MATR of RF, VL, and VM correlated with both functional tests (p < 0.05).</p><p><strong>Discussion: </strong>Muscle architecture alterations correlated with functional test results in patients with KOA. Understanding the influence of muscle architecture on functional parameters can facilitate the development of effective rehabilitation strategies to preserve and optimize patient function before it becomes compromised.</p><p><strong>Trial registration: </strong>Enrolled in clinical trials and awaiting approval.</p>","PeriodicalId":47243,"journal":{"name":"Physiotherapy Research International","volume":"30 2","pages":"e70030"},"PeriodicalIF":1.5000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Role of Muscle Architecture as a Determinant of Functional Performance in Women With Knee Osteoarthritis.\",\"authors\":\"Nazli Cigercioglu, Zilan Bazancir-Apaydin, Ezgi Unuvar-Yuksel, Hakan Apaydin, Gul Baltaci, Hande Guney-Deniz\",\"doi\":\"10.1002/pri.70030\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and purpose: </strong>Knee osteoarthritis (KOA) is associated with early muscular alterations and muscle weakness, which contribute to disease progression. However, limited knowledge exists regarding the potential exacerbation of lower extremity muscle architecture and its impact on functional performance. This study aimed to investigate the relationship between knee extensor and ankle plantar flexor muscle architecture, femoral cartilage thickness, age, body mass index (BMI), pain severity, and functional performance in middle-aged women with KOA.</p><p><strong>Methods: </strong>A total of 87 patients diagnosed with KOA (mean age = 51.48 ± 4.89 years, mean BMI = 27.96 ± 4.66 kg/m<sup>2</sup>) were included in the study. Ultrasonography was used to assess muscle thickness, adipose tissue thickness, pennation angle, and the muscle/adipose tissue thickness ratio (MATR) of the Rectus Femoris (RF), Vastus Medialis (VM), Vastus Lateralis (VL), and Medial Gastrocnemius (MG) muscles. Physical performance was evaluated through the stair-climbing test and the 10-time sit to stand test. Pearson's correlation test and multiple linear regression analysis were used.</p><p><strong>Results: </strong>The pennation angle of the VL and pain level predicted sit to stand test results; the pennation angle of RF, age, BMI and pain level predicted stair-climbing test results (p < 0.001). Femoral cartilage thickness at the medial condyle, intercondylar area, and lateral condyle correlated with performance in both tests (p < 0.001). Additionally, age, BMI, pain intensity, muscle thickness, pennation angle and MATR of RF, VL, and VM correlated with both functional tests (p < 0.05).</p><p><strong>Discussion: </strong>Muscle architecture alterations correlated with functional test results in patients with KOA. Understanding the influence of muscle architecture on functional parameters can facilitate the development of effective rehabilitation strategies to preserve and optimize patient function before it becomes compromised.</p><p><strong>Trial registration: </strong>Enrolled in clinical trials and awaiting approval.</p>\",\"PeriodicalId\":47243,\"journal\":{\"name\":\"Physiotherapy Research International\",\"volume\":\"30 2\",\"pages\":\"e70030\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physiotherapy Research International\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/pri.70030\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"REHABILITATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiotherapy Research International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/pri.70030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"REHABILITATION","Score":null,"Total":0}
The Role of Muscle Architecture as a Determinant of Functional Performance in Women With Knee Osteoarthritis.
Background and purpose: Knee osteoarthritis (KOA) is associated with early muscular alterations and muscle weakness, which contribute to disease progression. However, limited knowledge exists regarding the potential exacerbation of lower extremity muscle architecture and its impact on functional performance. This study aimed to investigate the relationship between knee extensor and ankle plantar flexor muscle architecture, femoral cartilage thickness, age, body mass index (BMI), pain severity, and functional performance in middle-aged women with KOA.
Methods: A total of 87 patients diagnosed with KOA (mean age = 51.48 ± 4.89 years, mean BMI = 27.96 ± 4.66 kg/m2) were included in the study. Ultrasonography was used to assess muscle thickness, adipose tissue thickness, pennation angle, and the muscle/adipose tissue thickness ratio (MATR) of the Rectus Femoris (RF), Vastus Medialis (VM), Vastus Lateralis (VL), and Medial Gastrocnemius (MG) muscles. Physical performance was evaluated through the stair-climbing test and the 10-time sit to stand test. Pearson's correlation test and multiple linear regression analysis were used.
Results: The pennation angle of the VL and pain level predicted sit to stand test results; the pennation angle of RF, age, BMI and pain level predicted stair-climbing test results (p < 0.001). Femoral cartilage thickness at the medial condyle, intercondylar area, and lateral condyle correlated with performance in both tests (p < 0.001). Additionally, age, BMI, pain intensity, muscle thickness, pennation angle and MATR of RF, VL, and VM correlated with both functional tests (p < 0.05).
Discussion: Muscle architecture alterations correlated with functional test results in patients with KOA. Understanding the influence of muscle architecture on functional parameters can facilitate the development of effective rehabilitation strategies to preserve and optimize patient function before it becomes compromised.
Trial registration: Enrolled in clinical trials and awaiting approval.
期刊介绍：
Physiotherapy Research International is an international peer reviewed journal dedicated to the exchange of knowledge that is directly relevant to specialist areas of physiotherapy theory, practice, and research. Our aim is to promote a high level of scholarship and build on the current evidence base to inform the advancement of the physiotherapy profession. We publish original research on a wide range of topics e.g. Primary research testing new physiotherapy treatments; methodological research; measurement and outcome research and qualitative research of interest to researchers, clinicians and educators. Further, we aim to publish high quality papers that represent the range of cultures and settings where physiotherapy services are delivered. We attract a wide readership from physiotherapists and others working in diverse clinical and academic settings. We aim to promote an international debate amongst the profession about current best evidence based practice. Papers are directed primarily towards the physiotherapy profession, but can be relevant to a wide range of professional groups. The growth of interdisciplinary research is also key to our aims and scope, and we encourage relevant submissions from other professional groups. The journal actively encourages submissions which utilise a breadth of different methodologies and research designs to facilitate addressing key questions related to the physiotherapy practice. PRI seeks to encourage good quality topical debates on a range of relevant issues and promote critical reflection on decision making and implementation of physiotherapy interventions.
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