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IF 2.1 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Medical hypotheses Pub Date : 2025-01-01 DOI:10.1016/j.mehy.2024.111549

Yong Tang, Lei Zhou, Jihong Jiang, Yangsheng Wang, Changwei Chen, Feng Zhu

引用次数: 0

摘要

青少年特发性脊柱侧弯症（AIS）是一种三维脊柱畸形，其特点是一个或多个脊柱节段侧弯并伴有椎体旋转。它包括冠状面、矢状面和轴面异常，导致脊柱失去自然弯曲。这种病常见于 10 至 17 岁的青少年。尽管进行了广泛的研究，但 AIS 的发病机制仍然十分复杂。本文提出了一个新的假设，即单侧多裂肌发育不良可能会导致 AIS 的发生。我们回顾了有关 AIS 中多裂肌功能障碍的现有研究，并提出了支持我们假设的结果。要验证这一假设并探讨其对 AIS 诊断和管理的影响，还需要进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Unilateral multifidus hypoplasia as a potential cause of adolescent idiopathic scoliosis: A hypothesis

Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional spinal deformity featuring lateral curvature of one or more spine segments with vertebral rotation. It involves coronal, sagittal, and axial plane abnormalities, leading to the spine losing its natural curvature. It is commonly observed in adolescents aged 10 to 17. Despite extensive research, the pathogenesis of AIS remains complex. This paper proposes a novel hypothesis that unilateral hypoplasia of the multifidus muscle may contribute to the development of AIS. We review existing studies on multifidus muscle dysfunction in AIS and present results supporting our hypothesis. Further research is necessary to validate this hypothesis and explore its implications for the diagnosis and management of AIS.

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来源期刊

Medical hypotheses 医学-医学：研究与实验

CiteScore

10.60

自引率

2.10%

发文量

167

审稿时长

60 days

期刊介绍： Medical Hypotheses is a forum for ideas in medicine and related biomedical sciences. It will publish interesting and important theoretical papers that foster the diversity and debate upon which the scientific process thrives. The Aims and Scope of Medical Hypotheses are no different now from what was proposed by the founder of the journal, the late Dr David Horrobin. In his introduction to the first issue of the Journal, he asks ''what sorts of papers will be published in Medical Hypotheses? and goes on to answer ''Medical Hypotheses will publish papers which describe theories, ideas which have a great deal of observational support and some hypotheses where experimental support is yet fragmentary''. (Horrobin DF, 1975 Ideas in Biomedical Science: Reasons for the foundation of Medical Hypotheses. Medical Hypotheses Volume 1, Issue 1, January-February 1975, Pages 1-2.). Medical Hypotheses was therefore launched, and still exists today, to give novel, radical new ideas and speculations in medicine open-minded consideration, opening the field to radical hypotheses which would be rejected by most conventional journals. Papers in Medical Hypotheses take a standard scientific form in terms of style, structure and referencing. The journal therefore constitutes a bridge between cutting-edge theory and the mainstream of medical and scientific communication, which ideas must eventually enter if they are to be critiqued and tested against observations.