关节软骨重建的概念、技术、并发症、危险因素和救助策略综述

Q2 Medicine
Melanio Acosta IV, Alberto Gobbi
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引用次数: 0

摘要

软骨病变是困难和具有挑战性的取决于他们的大小,位置和慢性。在软骨重建中,我们的目标是使用技术来帮助保存关节,再生丢失或病变的软骨,并希望防止或延迟骨关节炎的进展和关节置换术的需要。由于患者和病变特征因病例而异,没有单一的手术策略可以治疗所有软骨病变。随着我们知识的进步和综合研究的努力,微骨折和微钻孔等骨髓刺激技术,以及自体软骨细胞植入、自体基质诱导软骨形成等软骨再生方法,以及透明质酸支架与MSCs的应用,已经成为应对这一日益增长的挑战的基本途径。强调患者选择的重要性是至关重要的,因为遵守康复和恢复比赛协议以及遵守既定时间表是至关重要的。此外,有必要选择那些没有生物力学失调的患者,并且没有在手术前必须解决的伴有半月板或韧带问题的患者。然而,尽管我们尽一切努力确保患者获得最佳结果,但有时并发症是不可避免的。因此,能够识别可能的并发症,利用策略来预防这些并发症,并知道如何处理遇到的并发症对任何骨科医生都很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complications in anterior cruciate ligament reconstruction Articular cartilage reconstruction: Review of concepts, techniques, complications, risk factors, and Bail out/salvage strategies
Chondral lesions are difficult and challenging depending on their size, location, and chronicity. In cartilage reconstruction, our aim is to employ techniques to help save the joint, regenerate lost or diseased cartilage, and hopefully prevent or delay the progression of osteoarthritis and the need for arthroplasty. As patient and lesion characteristics differ from case to case, there is no single surgical strategy ideal to treat all chondral lesions. With the advancement of our knowledge and comprehensive research efforts, marrow-stimulating techniques like microfracture and microdrilling, as well as cartilage regeneration methods such as autologous chondrocyte implantation, autologous matrix-induced chondrogenesis, and the application of hyaluronic acid-based scaffolds with MSCs, have become fundamental approaches in confronting this growing challenge. Emphasizing the importance of patient selection is vital, given that compliance with rehabilitation and return-to-play protocols, along with adherence to established timelines, is essential. Furthermore, it is necessary to select patients who are free from biomechanical malalignment and do not present with concomitant meniscal or ligamentous issues that must be addressed prior to surgery. However, despite all our attempts to ensure the best outcomes for our patients, complications are sometimes unavoidable. Thus, being able to recognize possible complications, utilize strategies to prevent these complications, and knowing how to manage complications when encountered are important for any orthopaedic surgeon.
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来源期刊
Journal of Clinical Orthopaedics and Trauma
Journal of Clinical Orthopaedics and Trauma Medicine-Orthopedics and Sports Medicine
CiteScore
4.30
自引率
0.00%
发文量
181
审稿时长
92 days
期刊介绍: Journal of Clinical Orthopaedics and Trauma (JCOT) aims to provide its readers with the latest clinical and basic research, and informed opinions that shape today''s orthopedic practice, thereby providing an opportunity to practice evidence-based medicine. With contributions from leading clinicians and researchers around the world, we aim to be the premier journal providing an international perspective advancing knowledge of the musculoskeletal system. JCOT publishes content of value to both general orthopedic practitioners and specialists on all aspects of musculoskeletal research, diagnoses, and treatment. We accept following types of articles: • Original articles focusing on current clinical issues. • Review articles with learning value for professionals as well as students. • Research articles providing the latest in basic biological or engineering research on musculoskeletal diseases. • Regular columns by experts discussing issues affecting the field of orthopedics. • "Symposia" devoted to a single topic offering the general reader an overview of a field, but providing the specialist current in-depth information. • Video of any orthopedic surgery which is innovative and adds to present concepts. • Articles emphasizing or demonstrating a new clinical sign in the art of patient examination is also considered for publication. Contributions from anywhere in the world are welcome and considered on their merits.
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